abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGDSVQAGGSLKLSCAASGYIFS	1 - 30	30
CDR-H1	TCGMG	31 - 35	5
HFR2	WYRQAPGKERELLS	36 - 49	14
CDR-H2	TRSIDGTTRYADSVKG	50 - 65	16
HFR3	RFTISQDRAKHTLYLQMNSLKTEDTAVYYCRA	66 - 97	32
CDR-H3	GGGSGSWCPGNY	98 - 109	12
HFR4	WGQGTQVTVSS	110 - 120	11
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGDSVQAGGSLKLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGDSVQAGGSLKLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGDSVQAGGSLKLSCAASGYIFS	1 - 30	30
	Contact	QVQLQESGGDSVQAGGSLKLSCAASGYIF-	1 - 29	29
	IMGT	QVQLQESGGDSVQAGGSLKLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GYIFSTC---	26 - 32	7
	AbM	GYIFSTCGMG	26 - 35	10
	Kabat	-----TCGMG	31 - 35	5
	Contact	----STCGMG	30 - 35	6
	IMGT	GYIFSTCG--	26 - 33	8
HFR2	Chothia	GMGWYRQAPGKERELLSTR	33 - 51	19
	AbM	---WYRQAPGKERELLS--	36 - 49	14
	Kabat	---WYRQAPGKERELLS--	36 - 49	14
	Contact	---WYRQAPGKERE-----	36 - 46	11
	IMGT	-MGWYRQAPGKERELLST-	34 - 50	17
CDR-H2	Chothia	-----SIDGT---------	52 - 56	5
	AbM	---TRSIDGTTR-------	50 - 58	9
	Kabat	---TRSIDGTTRYADSVKG	50 - 65	16
	Contact	LLSTRSIDGTTR-------	47 - 58	12
	IMGT	----RSIDGTT--------	51 - 57	7
HFR3	Chothia	TRYADSVKGRFTISQDRAKHTLYLQMNSLKTEDTAVYYCRA	57 - 97	41
	AbM	--YADSVKGRFTISQDRAKHTLYLQMNSLKTEDTAVYYCRA	59 - 97	39
	Kabat	---------RFTISQDRAKHTLYLQMNSLKTEDTAVYYCRA	66 - 97	32
	Contact	--YADSVKGRFTISQDRAKHTLYLQMNSLKTEDTAVYYC--	59 - 95	37
	IMGT	-RYADSVKGRFTISQDRAKHTLYLQMNSLKTEDTAVYYC--	58 - 95	38
CDR-H3	Chothia	--GGGSGSWCPGNY	98 - 109	12
	AbM	--GGGSGSWCPGNY	98 - 109	12
	Kabat	--GGGSGSWCPGNY	98 - 109	12
	Contact	RAGGGSGSWCPGN-	96 - 108	13
	IMGT	RAGGGSGSWCPGNY	96 - 109	14
HFR4	Chothia	-WGQGTQVTVSS	110 - 120	11
	AbM	-WGQGTQVTVSS	110 - 120	11
	Kabat	-WGQGTQVTVSS	110 - 120	11
	Contact	YWGQGTQVTVSS	109 - 120	12
	IMGT	-WGQGTQVTVSS	110 - 120	11

Accession & Annotations

Accession	ALN98712.1
Source	abYsis-EMBL-IG KT428336 Submitted 23-NOV-2015 Updated 23-JUN-2016
Name	immunoglobulin heavy chain variable region
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Liu H., Wang Y., Duan H., Zhang A., Liang C., Gao J., Zhang C., Huang B., Li Q., Li N., Xiao S., Zhou E.M. 'An intracellularly expressed Nsp9-specific nanobody in MARC-145 cells inhibits porcine reproductive and respiratory syndrome virus replication' Vet. Microbiol. 181(3-4):252-260(2015). Liu H., Xiao S., Wang Y., Duan H., Zhou E.-M. Submitted (14-AUG-2015) to the INSDC. College of Veterinary Medicine, Northwest A&F University, Xinong Road 22, Yangling, Shaanxi 712100, China

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGDSVQAGGSLKLSCAASGYIFSTCGMGWYRQAPGKERELLSTRSIDGTTRYA
DSVKGRFTISQDRAKHTLYLQMNSLKTEDTAVYYCRAGGGSGSWCPGNYWGQGTQVTVSS

DNA Sequence:

caggtccaactgcaggagtctgggggagactcggtgcaggctggagggtctctgaaactc
tcctgtgcagcctctggatacatcttcagtacatgtggaatgggctggtaccgccaggca
ccagggaaggagcgcgagttgctctcaactcgtagtattgatggtaccacaagatatgca
gactccgtgaagggccgattcaccatctcccaagaccgtgccaagcacacgctgtatctg
caaatgaacagcctgaaaactgaggacacggccgtgtattactgtcgggcagggggaggc
tcaggctcttggtgccccggtaactactggggccagggaacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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