abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQSGGSLRLSCVASGYRLN	1 - 30	30
CDR-H1	LNCMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	TIASDSYGRYADSVRG	50 - 65	16
HFR3	RFAISQDNAKNTLYLQMNTLNPEDTATYYCAA	66 - 97	32
CDR-H3	WRGDCGIPDMLRTDNY	98 - 113	16
HFR4	RGQGTQVTVSS	114 - 124	11
			124

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQSGGSLRLSCVAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQSGGSLRLSCVAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQSGGSLRLSCVASGYRLN	1 - 30	30
	Contact	QVQLQESGGGSVQSGGSLRLSCVASGYRL-	1 - 29	29
	IMGT	QVQLQESGGGSVQSGGSLRLSCVAS-----	1 - 25	25
CDR-H1	Chothia	GYRLNLN---	26 - 32	7
	AbM	GYRLNLNCMG	26 - 35	10
	Kabat	-----LNCMG	31 - 35	5
	Contact	----NLNCMG	30 - 35	6
	IMGT	GYRLNLNC--	26 - 33	8
HFR2	Chothia	CMGWFRQAPGKEREGVATI	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAT-	34 - 50	17
CDR-H2	Chothia	-----ASDSY---------	52 - 56	5
	AbM	---TIASDSYGR-------	50 - 58	9
	Kabat	---TIASDSYGRYADSVRG	50 - 65	16
	Contact	GVATIASDSYGR-------	47 - 58	12
	IMGT	----IASDSYG--------	51 - 57	7
HFR3	Chothia	GRYADSVRGRFAISQDNAKNTLYLQMNTLNPEDTATYYCAA	57 - 97	41
	AbM	--YADSVRGRFAISQDNAKNTLYLQMNTLNPEDTATYYCAA	59 - 97	39
	Kabat	---------RFAISQDNAKNTLYLQMNTLNPEDTATYYCAA	66 - 97	32
	Contact	--YADSVRGRFAISQDNAKNTLYLQMNTLNPEDTATYYC--	59 - 95	37
	IMGT	-RYADSVRGRFAISQDNAKNTLYLQMNTLNPEDTATYYC--	58 - 95	38
CDR-H3	Chothia	--WRGDCGIPDMLRTDNY	98 - 113	16
	AbM	--WRGDCGIPDMLRTDNY	98 - 113	16
	Kabat	--WRGDCGIPDMLRTDNY	98 - 113	16
	Contact	AAWRGDCGIPDMLRTDN-	96 - 112	17
	IMGT	AAWRGDCGIPDMLRTDNY	96 - 113	18
HFR4	Chothia	-RGQGTQVTVSS	114 - 124	11
	AbM	-RGQGTQVTVSS	114 - 124	11
	Kabat	-RGQGTQVTVSS	114 - 124	11
	Contact	YRGQGTQVTVSS	113 - 124	12
	IMGT	-RGQGTQVTVSS	114 - 124	11

Accession & Annotations

Accession	ALN98714.1
Source	abYsis-EMBL-IG KT428338 Submitted 23-NOV-2015 Updated 23-JUN-2016
Name	immunoglobulin heavy chain variable region
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Liu H., Wang Y., Duan H., Zhang A., Liang C., Gao J., Zhang C., Huang B., Li Q., Li N., Xiao S., Zhou E.M. 'An intracellularly expressed Nsp9-specific nanobody in MARC-145 cells inhibits porcine reproductive and respiratory syndrome virus replication' Vet. Microbiol. 181(3-4):252-260(2015). Liu H., Xiao S., Wang Y., Duan H., Zhou E.-M. Submitted (14-AUG-2015) to the INSDC. College of Veterinary Medicine, Northwest A&F University, Xinong Road 22, Yangling, Shaanxi 712100, China

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQSGGSLRLSCVASGYRLNLNCMGWFRQAPGKEREGVATIASDSYGRYA
DSVRGRFAISQDNAKNTLYLQMNTLNPEDTATYYCAAWRGDCGIPDMLRTDNYRGQGTQV
TVSS

DNA Sequence:

caggtccaactgcaggagtctgggggaggctcggtgcagtctggagggtctctaagactc
tcctgtgtagcctctggataccgcctcaatttaaactgcatgggctggttccgccaggct
cctggaaaggagcgcgagggggtcgcaactattgcaagtgattcgtatgggaggtacgca
gactccgtgaggggccgattcgccatctcccaagacaacgccaagaacacgctgtacctg
caaatgaacaccctgaaccctgaggacacggccacgtattattgtgcggcctggcgggga
gattgtggcataccggatatgttaagaaccgacaactaccggggccaggggacccaggtc
accgtctcctca

Data Source:

Alignment settings:

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