abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
CDR-H1	SYDMH	31 - 35	5
HFR2	WVRQAPGKGLEWVS	36 - 49	14
CDR-H2	RINRHGTTTYYADSVKG	50 - 66	17
HFR3	RFTISRDNAKNMLYLQLNSLNTEDTAMYYCAR	67 - 98	32
CDR-H3	DSPIGWSGNND	99 - 109	11
HFR4	RGQGTQVTVSS	110 - 120	11
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
	Contact	QVQLQESGGGLVQPGGSLRLSCAASGFTF-	1 - 29	29
	IMGT	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GFTFSSY---	26 - 32	7
	AbM	GFTFSSYDMH	26 - 35	10
	Kabat	-----SYDMH	31 - 35	5
	Contact	----SSYDMH	30 - 35	6
	IMGT	GFTFSSYD--	26 - 33	8
HFR2	Chothia	DMHWVRQAPGKGLEWVSRI	33 - 51	19
	AbM	---WVRQAPGKGLEWVS--	36 - 49	14
	Kabat	---WVRQAPGKGLEWVS--	36 - 49	14
	Contact	---WVRQAPGKGLE-----	36 - 46	11
	IMGT	-MHWVRQAPGKGLEWVSR-	34 - 50	17
CDR-H2	Chothia	-----NRHGTT---------	52 - 57	6
	AbM	---RINRHGTTTY-------	50 - 59	10
	Kabat	---RINRHGTTTYYADSVKG	50 - 66	17
	Contact	WVSRINRHGTTTY-------	47 - 59	13
	IMGT	----INRHGTTT--------	51 - 58	8
HFR3	Chothia	TYYADSVKGRFTISRDNAKNMLYLQLNSLNTEDTAMYYCAR	58 - 98	41
	AbM	--YADSVKGRFTISRDNAKNMLYLQLNSLNTEDTAMYYCAR	60 - 98	39
	Kabat	---------RFTISRDNAKNMLYLQLNSLNTEDTAMYYCAR	67 - 98	32
	Contact	--YADSVKGRFTISRDNAKNMLYLQLNSLNTEDTAMYYC--	60 - 96	37
	IMGT	-YYADSVKGRFTISRDNAKNMLYLQLNSLNTEDTAMYYC--	59 - 96	38
CDR-H3	Chothia	--DSPIGWSGNND	99 - 109	11
	AbM	--DSPIGWSGNND	99 - 109	11
	Kabat	--DSPIGWSGNND	99 - 109	11
	Contact	ARDSPIGWSGNN-	97 - 108	12
	IMGT	ARDSPIGWSGNND	97 - 109	13
HFR4	Chothia	-RGQGTQVTVSS	110 - 120	11
	AbM	-RGQGTQVTVSS	110 - 120	11
	Kabat	-RGQGTQVTVSS	110 - 120	11
	Contact	DRGQGTQVTVSS	109 - 120	12
	IMGT	-RGQGTQVTVSS	110 - 120	11

Accession & Annotations

Accession	ALN98716.1
Source	abYsis-EMBL-IG KT428340 Submitted 23-NOV-2015 Updated 23-JUN-2016
Name	immunoglobulin heavy chain variable region
Organism	Camelus bactrianus
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Liu H., Wang Y., Duan H., Zhang A., Liang C., Gao J., Zhang C., Huang B., Li Q., Li N., Xiao S., Zhou E.M. 'An intracellularly expressed Nsp9-specific nanobody in MARC-145 cells inhibits porcine reproductive and respiratory syndrome virus replication' Vet. Microbiol. 181(3-4):252-260(2015). Liu H., Xiao S., Wang Y., Duan H., Zhou E.-M. Submitted (14-AUG-2015) to the INSDC. College of Veterinary Medicine, Northwest A&F University, Xinong Road 22, Yangling, Shaanxi 712100, China

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQPGGSLRLSCAASGFTFSSYDMHWVRQAPGKGLEWVSRINRHGTTTYY
ADSVKGRFTISRDNAKNMLYLQLNSLNTEDTAMYYCARDSPIGWSGNNDRGQGTQVTVSS

DNA Sequence:

caggtccaactgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactc
tcctgtgcagcctctggcttcaccttcagtagctatgacatgcactgggtccgccaggct
ccagggaagggactcgagtgggtctcacgtattaatagacatggtactacgacatactat
gcagactccgtgaagggccgattcaccatctccagagacaacgccaagaacatgctgtat
ctgcaattgaacagcctgaacacggaggacacggctatgtattactgtgcaagagattcg
ccaattggttggtctgggaataatgaccggggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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