abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
CDR-H1	SHWMY	31 - 35	5
HFR2	WVRQAPGKGLEWVS	36 - 49	14
CDR-H2	SISFDGDTYYADSVKG	50 - 65	16
HFR3	RFTISRDIAKNTLYLQMNSLKSDDTALYYCTT	66 - 97	32
CDR-H3	DRRGAGK	98 - 104	7
HFR4	RGQGTQVTVSS	105 - 115	11
			115

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
	Contact	QVQLQESGGGLVQPGGSLRLSCAASGFTF-	1 - 29	29
	IMGT	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GFTFSSH---	26 - 32	7
	AbM	GFTFSSHWMY	26 - 35	10
	Kabat	-----SHWMY	31 - 35	5
	Contact	----SSHWMY	30 - 35	6
	IMGT	GFTFSSHW--	26 - 33	8
HFR2	Chothia	WMYWVRQAPGKGLEWVSSI	33 - 51	19
	AbM	---WVRQAPGKGLEWVS--	36 - 49	14
	Kabat	---WVRQAPGKGLEWVS--	36 - 49	14
	Contact	---WVRQAPGKGLE-----	36 - 46	11
	IMGT	-MYWVRQAPGKGLEWVSS-	34 - 50	17
CDR-H2	Chothia	-----SFDGD---------	52 - 56	5
	AbM	---SISFDGDTY-------	50 - 58	9
	Kabat	---SISFDGDTYYADSVKG	50 - 65	16
	Contact	WVSSISFDGDTY-------	47 - 58	12
	IMGT	----ISFDGDT--------	51 - 57	7
HFR3	Chothia	TYYADSVKGRFTISRDIAKNTLYLQMNSLKSDDTALYYCTT	57 - 97	41
	AbM	--YADSVKGRFTISRDIAKNTLYLQMNSLKSDDTALYYCTT	59 - 97	39
	Kabat	---------RFTISRDIAKNTLYLQMNSLKSDDTALYYCTT	66 - 97	32
	Contact	--YADSVKGRFTISRDIAKNTLYLQMNSLKSDDTALYYC--	59 - 95	37
	IMGT	-YYADSVKGRFTISRDIAKNTLYLQMNSLKSDDTALYYC--	58 - 95	38
CDR-H3	Chothia	--DRRGAGK	98 - 104	7
	AbM	--DRRGAGK	98 - 104	7
	Kabat	--DRRGAGK	98 - 104	7
	Contact	TTDRRGAG-	96 - 103	8
	IMGT	TTDRRGAGK	96 - 104	9
HFR4	Chothia	-RGQGTQVTVSS	105 - 115	11
	AbM	-RGQGTQVTVSS	105 - 115	11
	Kabat	-RGQGTQVTVSS	105 - 115	11
	Contact	KRGQGTQVTVSS	104 - 115	12
	IMGT	-RGQGTQVTVSS	105 - 115	11

Accession & Annotations

Accession	AUS94284.1
Source	abYsis-EMBL-IG MF001026 Submitted 31-JAN-2018 Updated 31-JAN-2018
Name	anti-BBMV nanobody immunoglobulin heavy chain variable region
Clone	NbBBMV10
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Ghannam A., Kumari S., Muyldermans S., Abbady A.Q. 'Camelid nanobodies with high affinity for broad bean mottle virus: a possible promising tool to immunomodulate plant resistance against viruses' Plant Mol. Biol. 87(4-5):355-369(2015). Abbady A.Q. Submitted (27-APR-2017) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQPGGSLRLSCAASGFTFSSHWMYWVRQAPGKGLEWVSSISFDGDTYYA
DSVKGRFTISRDIAKNTLYLQMNSLKSDDTALYYCTTDRRGAGKRGQGTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctgggggaggcttggtgcagcctggggggtctctgagactc
tcctgtgcagcctctggattcaccttcagtagccactggatgtactgggtccgccaggct
ccagggaaggggctcgagtgggtctcaagtattagttttgatggtgacacatactatgca
gactccgtgaagggccgattcaccatctccagagacatcgccaagaacacgctgtatctg
caaatgaacagcctgaaatctgacgacacggccctatattactgtactacagatcgtaga
ggcgcaggaaaacggggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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