abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQSGGSLRLSCAASGFPVS	1 - 30	30
CDR-H1	SHWMY	31 - 35	5
HFR2	WVRQAPGKGFEWVS	36 - 49	14
CDR-H2	SIDSGDGHTYYADSVKG	50 - 66	17
HFR3	RFTISRGNAENTVYLQLNSLKTEDTAMYYCTT	67 - 98	32
CDR-H3	DRNRALP	99 - 105	7
HFR4	RGQGTQVTVSS	106 - 116	11
			116

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQSGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQSGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQSGGSLRLSCAASGFPVS	1 - 30	30
	Contact	QVQLQESGGGLVQSGGSLRLSCAASGFPV-	1 - 29	29
	IMGT	QVQLQESGGGLVQSGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GFPVSSH---	26 - 32	7
	AbM	GFPVSSHWMY	26 - 35	10
	Kabat	-----SHWMY	31 - 35	5
	Contact	----SSHWMY	30 - 35	6
	IMGT	GFPVSSHW--	26 - 33	8
HFR2	Chothia	WMYWVRQAPGKGFEWVSSI	33 - 51	19
	AbM	---WVRQAPGKGFEWVS--	36 - 49	14
	Kabat	---WVRQAPGKGFEWVS--	36 - 49	14
	Contact	---WVRQAPGKGFE-----	36 - 46	11
	IMGT	-MYWVRQAPGKGFEWVSS-	34 - 50	17
CDR-H2	Chothia	-----DSGDGH---------	52 - 57	6
	AbM	---SIDSGDGHTY-------	50 - 59	10
	Kabat	---SIDSGDGHTYYADSVKG	50 - 66	17
	Contact	WVSSIDSGDGHTY-------	47 - 59	13
	IMGT	----IDSGDGHT--------	51 - 58	8
HFR3	Chothia	TYYADSVKGRFTISRGNAENTVYLQLNSLKTEDTAMYYCTT	58 - 98	41
	AbM	--YADSVKGRFTISRGNAENTVYLQLNSLKTEDTAMYYCTT	60 - 98	39
	Kabat	---------RFTISRGNAENTVYLQLNSLKTEDTAMYYCTT	67 - 98	32
	Contact	--YADSVKGRFTISRGNAENTVYLQLNSLKTEDTAMYYC--	60 - 96	37
	IMGT	-YYADSVKGRFTISRGNAENTVYLQLNSLKTEDTAMYYC--	59 - 96	38
CDR-H3	Chothia	--DRNRALP	99 - 105	7
	AbM	--DRNRALP	99 - 105	7
	Kabat	--DRNRALP	99 - 105	7
	Contact	TTDRNRAL-	97 - 104	8
	IMGT	TTDRNRALP	97 - 105	9
HFR4	Chothia	-RGQGTQVTVSS	106 - 116	11
	AbM	-RGQGTQVTVSS	106 - 116	11
	Kabat	-RGQGTQVTVSS	106 - 116	11
	Contact	PRGQGTQVTVSS	105 - 116	12
	IMGT	-RGQGTQVTVSS	106 - 116	11

Accession & Annotations

Accession	AUS94295.1
Source	abYsis-EMBL-IG MF001037 Submitted 31-JAN-2018 Updated 31-JAN-2018
Name	anti-BBMV nanobody immunoglobulin heavy chain variable region
Clone	NbBBMV30
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Ghannam A., Kumari S., Muyldermans S., Abbady A.Q. 'Camelid nanobodies with high affinity for broad bean mottle virus: a possible promising tool to immunomodulate plant resistance against viruses' Plant Mol. Biol. 87(4-5):355-369(2015). Abbady A.Q. Submitted (27-APR-2017) to the INSDC. Molecular Biology and Biotechnology, Atomic Energy Commission, Kafar-Souseh, Damascus 6091, Syria

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQSGGSLRLSCAASGFPVSSHWMYWVRQAPGKGFEWVSSIDSGDGHTYY
ADSVKGRFTISRGNAENTVYLQLNSLKTEDTAMYYCTTDRNRALPRGQGTQVTVSS

DNA Sequence:

caggtgcagctgcaggagtctggaggaggcttggtgcagtctggggggtctctgagactc
tcctgtgcagcctctggattccccgtcagtagccactggatgtactgggtccgccaggct
ccagggaagggtttcgagtgggtttcatctattgatagtggtgatggtcacacgtactat
gcagactccgtcaagggccgattcaccatctccagaggcaacgccgagaacacggtgtat
ctgcaattgaacagcctgaaaactgaggacacggccatgtattactgtacaacagaccgc
aaccgtgccctaccgaggggccaggggacccaggtcaccgtctcctca

Data Source:

Alignment settings:

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