abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	GST	1 - 3	3
HFR1	QVQLAETGGGLAQPGGSLRLSCAASGFTFS	4 - 33	30
CDR-H1	RAVMN	34 - 38	5
HFR2	WYRQAPGKERELVA	39 - 52	14
CDR-H2	RIYDAGGNGSIADPVKG	53 - 69	17
HFR3	RFTISRDNAKNTVHLQMNSLKPEDTAMYVCNA	70 - 101	32
CDR-H3	GIFDGNYRTY	102 - 111	10
HFR4	WGQGTQVTVSS	112 - 122	11
Tail	EPKTPKPQPARQGAPVPYPDPLEP	122 - 146	24
			146

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLAETGGGLAQPGGSLRLSCAAS-----	4 - 28	25
	AbM	QVQLAETGGGLAQPGGSLRLSCAAS-----	4 - 28	25
	Kabat	QVQLAETGGGLAQPGGSLRLSCAASGFTFS	4 - 33	30
	Contact	QVQLAETGGGLAQPGGSLRLSCAASGFTF-	4 - 32	29
	IMGT	QVQLAETGGGLAQPGGSLRLSCAAS-----	4 - 28	25
CDR-H1	Chothia	GFTFSRA---	29 - 35	7
	AbM	GFTFSRAVMN	29 - 38	10
	Kabat	-----RAVMN	34 - 38	5
	Contact	----SRAVMN	33 - 38	6
	IMGT	GFTFSRAV--	29 - 36	8
HFR2	Chothia	VMNWYRQAPGKERELVARI	36 - 54	19
	AbM	---WYRQAPGKERELVA--	39 - 52	14
	Kabat	---WYRQAPGKERELVA--	39 - 52	14
	Contact	---WYRQAPGKERE-----	39 - 49	11
	IMGT	-MNWYRQAPGKERELVAR-	37 - 53	17
CDR-H2	Chothia	-----YDAGGN---------	55 - 60	6
	AbM	---RIYDAGGNGS-------	53 - 62	10
	Kabat	---RIYDAGGNGSIADPVKG	53 - 69	17
	Contact	LVARIYDAGGNGS-------	50 - 62	13
	IMGT	----IYDAGGNG--------	54 - 61	8
HFR3	Chothia	GSIADPVKGRFTISRDNAKNTVHLQMNSLKPEDTAMYVCNA	61 - 101	41
	AbM	--IADPVKGRFTISRDNAKNTVHLQMNSLKPEDTAMYVCNA	63 - 101	39
	Kabat	---------RFTISRDNAKNTVHLQMNSLKPEDTAMYVCNA	70 - 101	32
	Contact	--IADPVKGRFTISRDNAKNTVHLQMNSLKPEDTAMYVC--	63 - 99	37
	IMGT	-SIADPVKGRFTISRDNAKNTVHLQMNSLKPEDTAMYVC--	62 - 99	38
CDR-H3	Chothia	--GIFDGNYRTY	102 - 111	10
	AbM	--GIFDGNYRTY	102 - 111	10
	Kabat	--GIFDGNYRTY	102 - 111	10
	Contact	NAGIFDGNYRT-	100 - 110	11
	IMGT	NAGIFDGNYRTY	100 - 111	12
HFR4	Chothia	-WGQGTQVTVSS	112 - 122	11
	AbM	-WGQGTQVTVSS	112 - 122	11
	Kabat	-WGQGTQVTVSS	112 - 122	11
	Contact	YWGQGTQVTVSS	111 - 122	12
	IMGT	-WGQGTQVTVSS	112 - 122	11

Accession & Annotations

Accession	5vxj_D
Source	PDB 5vxj Submitted 23-MAY-2017 Updated 30-AUG-2017
Name	2.50 A RESOLUTION STRUCTURE OF IPAD FROM SHIGELLA FLEXNERI IN COMPLEX WITH SINGLE-DOMAIN ANTIBODY JMK-E3
Organism	Vicugna pacos
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5vxj_B 5vxj_F 5vxj_H 5vxj_J
References	BARTA L., LOVELL S., BATTAILE P., PICKING D., PICKING L. '2.50 A RESOLUTION STRUCTURE OF IPAD FROM SHIGELLA FLEXNERI IN COMPLEX WITH SINGLE-DOMAIN ANTIBODY JMK-E3' TO BE PUBLISHED

Tools

Sequences

Amino Acid Sequence:

GSTQVQLAETGGGLAQPGGSLRLSCAASGFTFSRAVMNWYRQAPGKERELVARIYDAGGN
GSIADPVKGRFTISRDNAKNTVHLQMNSLKPEDTAMYVCNAGIFDGNYRTYWGQGTQVTV
SSEPKTPKPQPARQGAPVPYPDPLEP