abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	KVQLQESGGGLVQAGGSLRLSCAASGITFG	1 - 30	30
CDR-H1	RNIRR	31 - 35	5
HFR2	WYRQGSGKQRELVA	36 - 49	14
CDR-H2	SIDSWGTTAYAASVKG	50 - 65	16
HFR3	RFTISRDNGENTVYLQMNSLKPEDTAVYTCNA	66 - 97	32
CDR-H3	VSPRYPYTTY	98 - 107	10
HFR4	WGQGTQVTISA	108 - 118	11
			118

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	KVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	KVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	KVQLQESGGGLVQAGGSLRLSCAASGITFG	1 - 30	30
	Contact	KVQLQESGGGLVQAGGSLRLSCAASGITF-	1 - 29	29
	IMGT	KVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GITFGRN---	26 - 32	7
	AbM	GITFGRNIRR	26 - 35	10
	Kabat	-----RNIRR	31 - 35	5
	Contact	----GRNIRR	30 - 35	6
	IMGT	GITFGRNI--	26 - 33	8
HFR2	Chothia	IRRWYRQGSGKQRELVASI	33 - 51	19
	AbM	---WYRQGSGKQRELVA--	36 - 49	14
	Kabat	---WYRQGSGKQRELVA--	36 - 49	14
	Contact	---WYRQGSGKQRE-----	36 - 46	11
	IMGT	-RRWYRQGSGKQRELVAS-	34 - 50	17
CDR-H2	Chothia	-----DSWGT---------	52 - 56	5
	AbM	---SIDSWGTTA-------	50 - 58	9
	Kabat	---SIDSWGTTAYAASVKG	50 - 65	16
	Contact	LVASIDSWGTTA-------	47 - 58	12
	IMGT	----IDSWGTT--------	51 - 57	7
HFR3	Chothia	TAYAASVKGRFTISRDNGENTVYLQMNSLKPEDTAVYTCNA	57 - 97	41
	AbM	--YAASVKGRFTISRDNGENTVYLQMNSLKPEDTAVYTCNA	59 - 97	39
	Kabat	---------RFTISRDNGENTVYLQMNSLKPEDTAVYTCNA	66 - 97	32
	Contact	--YAASVKGRFTISRDNGENTVYLQMNSLKPEDTAVYTC--	59 - 95	37
	IMGT	-AYAASVKGRFTISRDNGENTVYLQMNSLKPEDTAVYTC--	58 - 95	38
CDR-H3	Chothia	--VSPRYPYTTY	98 - 107	10
	AbM	--VSPRYPYTTY	98 - 107	10
	Kabat	--VSPRYPYTTY	98 - 107	10
	Contact	NAVSPRYPYTT-	96 - 106	11
	IMGT	NAVSPRYPYTTY	96 - 107	12
HFR4	Chothia	-WGQGTQVTISA	108 - 118	11
	AbM	-WGQGTQVTISA	108 - 118	11
	Kabat	-WGQGTQVTISA	108 - 118	11
	Contact	YWGQGTQVTISA	107 - 118	12
	IMGT	-WGQGTQVTISA	108 - 118	11

Accession & Annotations

Accession	ATN23928.1
Source	abYsis-EMBL-IG MF780599 Submitted 28-OCT-2017 Updated 28-OCT-2017
Name	anti-Ebola Zaire virus nucleoprotein single domain antibody B
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Sherwood L.J., Hayhurst A. 'Ebolavirus nucleoprotein C-termini potently attract single domain antibodies enabling monoclonal affinity reagent sandwich assay (MARSA) formulation' PLoS One 8(4):E61232-E61232(2013). Sherwood L.J., Hayhurst A. Submitted (29-AUG-2017) to the INSDC. Virology and Immunology, Texas Biomedical Research Institute, 7620 NW Loop 410, San Antonio, TX 78227-5301, USA

Tools

Sequences

Amino Acid Sequence:

KVQLQESGGGLVQAGGSLRLSCAASGITFGRNIRRWYRQGSGKQRELVASIDSWGTTAYA
ASVKGRFTISRDNGENTVYLQMNSLKPEDTAVYTCNAVSPRYPYTTYWGQGTQVTISA

DNA Sequence:

aaggtccagctgcaggagtcagggggaggcttggtgcaggctgggggctctctgagactc
tcttgtgcagcctctggaatcaccttcggtcgcaatatcaggcgctggtaccgccagggt
tcagggaaacagcgcgaattggtcgcaagtattgatagttggggcaccacagcctatgca
gcctccgtgaagggccgattcaccatctccagggacaacggggagaacacggtgtatctg
caaatgaacagcctgaaacctgaggacacagccgtctatacctgtaatgcagtttctcca
aggtacccgtataccacctactggggccaggggacgcaggtcacaatctccgca

Data Source:

Alignment settings:

Search settings: