abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	MA	1 - 2	2
HFR1	QVQLVESGGGLVQAGDSLRLSCAASGLTFN	3 - 32	30
CDR-H1	RYNMG	33 - 37	5
HFR2	WFRQAPGREREFVA	38 - 51	14
CDR-H2	SISWSGDRTYGTDSVKG	52 - 68	17
HFR3	RFAISRDNAKNTMYLQMNSLKPEDTAVYYCAA	69 - 100	32
CDR-H3	DRFLTRSVKYDY	101 - 112	12
HFR4	WGQGTQVTVSS	113 - 123	11
Tail	HHHHHH	123 - 129	6
			129

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLVESGGGLVQAGDSLRLSCAAS-----	3 - 27	25
	AbM	QVQLVESGGGLVQAGDSLRLSCAAS-----	3 - 27	25
	Kabat	QVQLVESGGGLVQAGDSLRLSCAASGLTFN	3 - 32	30
	Contact	QVQLVESGGGLVQAGDSLRLSCAASGLTF-	3 - 31	29
	IMGT	QVQLVESGGGLVQAGDSLRLSCAAS-----	3 - 27	25
CDR-H1	Chothia	GLTFNRY---	28 - 34	7
	AbM	GLTFNRYNMG	28 - 37	10
	Kabat	-----RYNMG	33 - 37	5
	Contact	----NRYNMG	32 - 37	6
	IMGT	GLTFNRYN--	28 - 35	8
HFR2	Chothia	NMGWFRQAPGREREFVASI	35 - 53	19
	AbM	---WFRQAPGREREFVA--	38 - 51	14
	Kabat	---WFRQAPGREREFVA--	38 - 51	14
	Contact	---WFRQAPGRERE-----	38 - 48	11
	IMGT	-MGWFRQAPGREREFVAS-	36 - 52	17
CDR-H2	Chothia	-----SWSGDR---------	54 - 59	6
	AbM	---SISWSGDRTY-------	52 - 61	10
	Kabat	---SISWSGDRTYGTDSVKG	52 - 68	17
	Contact	FVASISWSGDRTY-------	49 - 61	13
	IMGT	----ISWSGDRT--------	53 - 60	8
HFR3	Chothia	TYGTDSVKGRFAISRDNAKNTMYLQMNSLKPEDTAVYYCAA	60 - 100	41
	AbM	--GTDSVKGRFAISRDNAKNTMYLQMNSLKPEDTAVYYCAA	62 - 100	39
	Kabat	---------RFAISRDNAKNTMYLQMNSLKPEDTAVYYCAA	69 - 100	32
	Contact	--GTDSVKGRFAISRDNAKNTMYLQMNSLKPEDTAVYYC--	62 - 98	37
	IMGT	-YGTDSVKGRFAISRDNAKNTMYLQMNSLKPEDTAVYYC--	61 - 98	38
CDR-H3	Chothia	--DRFLTRSVKYDY	101 - 112	12
	AbM	--DRFLTRSVKYDY	101 - 112	12
	Kabat	--DRFLTRSVKYDY	101 - 112	12
	Contact	AADRFLTRSVKYD-	99 - 111	13
	IMGT	AADRFLTRSVKYDY	99 - 112	14
HFR4	Chothia	-WGQGTQVTVSS	113 - 123	11
	AbM	-WGQGTQVTVSS	113 - 123	11
	Kabat	-WGQGTQVTVSS	113 - 123	11
	Contact	YWGQGTQVTVSS	112 - 123	12
	IMGT	-WGQGTQVTVSS	113 - 123	11

Accession & Annotations

Accession	6gzp_A
Source	PDB 6gzp Submitted 04-JUL-2018 Updated 01-MAY-2019
Name	LLAMA NANOBODY PORM_02 STRUCTURE DETERMINED AT ROOM TEMPERATURE BY IN- SITU DIFFRACTION IN CHIPX MICROFLUIDIC DEVICE
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5lmw_A
References	DE WIJN R., HENNING O., ROCHE J., ENGILBERGE S., BETAT H., MORL M., ROUSSEL A., GIRARD E., OLIERIC V., FOX C., BRILLET K., LORBER B., SAUTER C. 'NEW MICROFLUIDIC DESIGN FOR CRYSTALLIZATION OF BIOMOLECULES AND THEIR IN SITU ANALYSIS BY SERIAL CRYSTALLOGRAPHY' IUCRJ 2019 ESSN 2052-2525

Tools

Sequences

Amino Acid Sequence:

MAQVQLVESGGGLVQAGDSLRLSCAASGLTFNRYNMGWFRQAPGREREFVASISWSGDRT
YGTDSVKGRFAISRDNAKNTMYLQMNSLKPEDTAVYYCAADRFLTRSVKYDYWGQGTQVT
VSSHHHHHH