abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIQMTQSPSSLSASVGDRVTIAC	1 - 23	23
CDR-L1	RASQSISSYLN	24 - 34	11
LFR2	WYQQKPGKAPKLLIY	35 - 49	15
CDR-L2	AASSLQS	50 - 56	7
LFR3	GVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	57 - 88	32
CDR-L3	QQANSFPWT	89 - 97	9
LFR4	FGQGTKVDIKR	98 - 108	11
			108

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIQMTQSPSSLSASVGDRVTIAC------	1 - 23	23
	AbM	DIQMTQSPSSLSASVGDRVTIAC------	1 - 23	23
	Kabat	DIQMTQSPSSLSASVGDRVTIAC------	1 - 23	23
	Contact	DIQMTQSPSSLSASVGDRVTIACRASQSI	1 - 29	29
	IMGT	DIQMTQSPSSLSASVGDRVTIACRAS---	1 - 26	26
CDR-L1	Chothia	RASQSISSYLN--	24 - 34	11
	AbM	RASQSISSYLN--	24 - 34	11
	Kabat	RASQSISSYLN--	24 - 34	11
	Contact	------SSYLNWY	30 - 36	7
	IMGT	---QSISSY----	27 - 32	6
LFR2	Chothia	--WYQQKPGKAPKLLIY	35 - 49	15
	AbM	--WYQQKPGKAPKLLIY	35 - 49	15
	Kabat	--WYQQKPGKAPKLLIY	35 - 49	15
	Contact	----QQKPGKAPK----	37 - 45	9
	IMGT	LNWYQQKPGKAPKLLIY	33 - 49	17
CDR-L2	Chothia	----AASSLQS	50 - 56	7
	AbM	----AASSLQS	50 - 56	7
	Kabat	----AASSLQS	50 - 56	7
	Contact	LLIYAASSLQ-	46 - 55	10
	IMGT	----AA-----	50 - 51	2
LFR3	Chothia	-----GVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	57 - 88	32
	AbM	-----GVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	57 - 88	32
	Kabat	-----GVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	57 - 88	32
	Contact	----SGVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	56 - 88	33
	IMGT	SSLQSGVPSRFSGSGSGSDFTLTISSLQPEDFATYYC	52 - 88	37
CDR-L3	Chothia	QQANSFPWT	89 - 97	9
	AbM	QQANSFPWT	89 - 97	9
	Kabat	QQANSFPWT	89 - 97	9
	Contact	QQANSFPW-	89 - 96	8
	IMGT	QQANSFPWT	89 - 97	9
LFR4	Chothia	-FGQGTKVDIKR	98 - 108	11
	AbM	-FGQGTKVDIKR	98 - 108	11
	Kabat	-FGQGTKVDIKR	98 - 108	11
	Contact	TFGQGTKVDIKR	97 - 108	12
	IMGT	-FGQGTKVDIKR	98 - 108	11

Accession & Annotations

Accession	AAN28712.1
Source	abYsis-EMBL-IG AF538696 Submitted 01-OCT-2002 Updated 01-OCT-2002
Name	recombinant single chain Fv antibody PVA3.11
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Kang X.D., Huang G., Zhang L.L. Submitted (16-AUG-2002) to the INSDC. Nuclear Medicine, Renji Hospital, 145 Shandong Rd, Shanghai 200001, China Kang X.D., Huang G., Zhang L.L. 'Analysis of antibody gene rearrangement, usage, and specificity in patients with pemphigus vulgaris' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DIQMTQSPSSLSASVGDRVTIACRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPS
RFSGSGSGSDFTLTISSLQPEDFATYYCQQANSFPWTFGQGTKVDIKR

DNA Sequence:

gacatccagatgacccagtctccatcctccctgtctgcatctgtaggagacagagtcacc
atcgcttgccgggcaagtcagagcattagcagctatttaaattggtatcagcagaaacca
gggaaagcccctaagctcctgatctatgctgcatccagtttacaaagtggggtcccatca
aggttcagcggcagtggatctggctcagatttcactctcaccatcagcagcctgcagcct
gaagattttgcaacttactattgtcaacaggctaacagtttcccttggacgttcggccaa
gggaccaaagtggatatcaaacgt

Data Source:

Alignment settings:

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