abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	EIVLTQSPAIMSASPGERVTMTC	1 - 23	23
CDR-L1	SASSSIRYIY	24 - 33	10
LFR2	WYQQKPGSSPRLLIY	34 - 48	15
CDR-L2	DTSNVAP	49 - 55	7
LFR3	GVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	56 - 87	32
CDR-L3	QEWSGYPYT	88 - 96	9
LFR4	FGGGTKLELKR	97 - 107	11
			107

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	EIVLTQSPAIMSASPGERVTMTC------	1 - 23	23
	AbM	EIVLTQSPAIMSASPGERVTMTC------	1 - 23	23
	Kabat	EIVLTQSPAIMSASPGERVTMTC------	1 - 23	23
	Contact	EIVLTQSPAIMSASPGERVTMTCSASSSI	1 - 29	29
	IMGT	EIVLTQSPAIMSASPGERVTMTCSAS---	1 - 26	26
CDR-L1	Chothia	SASSSIRYIY--	24 - 33	10
	AbM	SASSSIRYIY--	24 - 33	10
	Kabat	SASSSIRYIY--	24 - 33	10
	Contact	------RYIYWY	30 - 35	6
	IMGT	---SSIRY----	27 - 31	5
LFR2	Chothia	--WYQQKPGSSPRLLIY	34 - 48	15
	AbM	--WYQQKPGSSPRLLIY	34 - 48	15
	Kabat	--WYQQKPGSSPRLLIY	34 - 48	15
	Contact	----QQKPGSSPR----	36 - 44	9
	IMGT	IYWYQQKPGSSPRLLIY	32 - 48	17
CDR-L2	Chothia	----DTSNVAP	49 - 55	7
	AbM	----DTSNVAP	49 - 55	7
	Kabat	----DTSNVAP	49 - 55	7
	Contact	LLIYDTSNVA-	45 - 54	10
	IMGT	----DT-----	49 - 50	2
LFR3	Chothia	-----GVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	56 - 87	32
	AbM	-----GVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	56 - 87	32
	Kabat	-----GVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	56 - 87	32
	Contact	----PGVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	55 - 87	33
	IMGT	SNVAPGVPFRLSGSGSGTSYSLTINRTEAEDAATYYC	51 - 87	37
CDR-L3	Chothia	QEWSGYPYT	88 - 96	9
	AbM	QEWSGYPYT	88 - 96	9
	Kabat	QEWSGYPYT	88 - 96	9
	Contact	QEWSGYPY-	88 - 95	8
	IMGT	QEWSGYPYT	88 - 96	9
LFR4	Chothia	-FGGGTKLELKR	97 - 107	11
	AbM	-FGGGTKLELKR	97 - 107	11
	Kabat	-FGGGTKLELKR	97 - 107	11
	Contact	TFGGGTKLELKR	96 - 107	12
	IMGT	-FGGGTKLELKR	97 - 107	11

Accession & Annotations

Accession	AAQ16204.1
Source	abYsis-EMBL-IG AY337619 Submitted 05-AUG-2003 Updated 23-MAR-2004
Name	immunoglobulin variable light chain scFv anti-CMV paratope
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Chua K.H., Tan C.S., Khalid N., Harikrishna J.A., Othman R.Y. 'Synthesis of a soluble flag-tagged single chain variable fragment (scFv) antibody targeting cucumber mosaic virus (CMV) coat protein' Asia Pac. J. Mol. Biol. Biotechnol. 11(2):93-100(2003). Chua K.H., Tan C.S., Khalid N., Harikrishna J.A., Othman R.Y. Submitted (09-JUL-2003) to the INSDC. Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Kuala Lumpur 50603, Malaysia

Tools

Sequences

Amino Acid Sequence:

EIVLTQSPAIMSASPGERVTMTCSASSSIRYIYWYQQKPGSSPRLLIYDTSNVAPGVPFR
LSGSGSGTSYSLTINRTEAEDAATYYCQEWSGYPYTFGGGTKLELKR

DNA Sequence:

gaaattgttctcacccagtctccagcaatcatgtctgcatctccaggggagagggtcacc
atgacctgcagtgccagctcaagtatacgttacatatattggtaccaacagaagcctgga
tcctcccccagactcctgatttatgacacatccaacgtggctcctggagtcccttttcgc
ctcagtggcagtgggtctgggacctcttattctctcacaatcaaccgaacggaggctgag
gatgctgccacttattactgccaggagtggagtggttatccgtacacgttcggagggggc
accaagctggagctcaaacgg

Data Source:

Alignment settings:

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