abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	EVNLVQSGTVLKGPSATVQISCVTSGYSLT	1 - 30	30
CDR-H1	NYGMY	31 - 35	5
HFR2	WIKQFSEKSLELVA	36 - 49	14
CDR-H2	YIFTGVNYNQHYTPKMKS	50 - 67	18
HFR3	KANFTKENANSSLYYMEIRNVTAEDTALYYCTW	68 - 100	33
CDR-H3	WGRSFQFLIWSLVQNPS	101 - 117	17
HFR4	WGTGTLVTVSS	118 - 128	11
			128

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	EVNLVQSGTVLKGPSATVQISCVTS-----	1 - 25	25
	AbM	EVNLVQSGTVLKGPSATVQISCVTS-----	1 - 25	25
	Kabat	EVNLVQSGTVLKGPSATVQISCVTSGYSLT	1 - 30	30
	Contact	EVNLVQSGTVLKGPSATVQISCVTSGYSL-	1 - 29	29
	IMGT	EVNLVQSGTVLKGPSATVQISCVTS-----	1 - 25	25
CDR-H1	Chothia	GYSLTNY---	26 - 32	7
	AbM	GYSLTNYGMY	26 - 35	10
	Kabat	-----NYGMY	31 - 35	5
	Contact	----TNYGMY	30 - 35	6
	IMGT	GYSLTNYG--	26 - 33	8
HFR2	Chothia	GMYWIKQFSEKSLELVAYI	33 - 51	19
	AbM	---WIKQFSEKSLELVA--	36 - 49	14
	Kabat	---WIKQFSEKSLELVA--	36 - 49	14
	Contact	---WIKQFSEKSLE-----	36 - 46	11
	IMGT	-MYWIKQFSEKSLELVAY-	34 - 50	17
CDR-H2	Chothia	-----FTGVNYN---------	52 - 58	7
	AbM	---YIFTGVNYNQH-------	50 - 60	11
	Kabat	---YIFTGVNYNQHYTPKMKS	50 - 67	18
	Contact	LVAYIFTGVNYNQH-------	47 - 60	14
	IMGT	----IFTGVNYNQ--------	51 - 59	9
HFR3	Chothia	QHYTPKMKSKANFTKENANSSLYYMEIRNVTAEDTALYYCTW	59 - 100	42
	AbM	--YTPKMKSKANFTKENANSSLYYMEIRNVTAEDTALYYCTW	61 - 100	40
	Kabat	---------KANFTKENANSSLYYMEIRNVTAEDTALYYCTW	68 - 100	33
	Contact	--YTPKMKSKANFTKENANSSLYYMEIRNVTAEDTALYYC--	61 - 98	38
	IMGT	-HYTPKMKSKANFTKENANSSLYYMEIRNVTAEDTALYYC--	60 - 98	39
CDR-H3	Chothia	--WGRSFQFLIWSLVQNPS	101 - 117	17
	AbM	--WGRSFQFLIWSLVQNPS	101 - 117	17
	Kabat	--WGRSFQFLIWSLVQNPS	101 - 117	17
	Contact	TWWGRSFQFLIWSLVQNP-	99 - 116	18
	IMGT	TWWGRSFQFLIWSLVQNPS	99 - 117	19
HFR4	Chothia	-WGTGTLVTVSS	118 - 128	11
	AbM	-WGTGTLVTVSS	118 - 128	11
	Kabat	-WGTGTLVTVSS	118 - 128	11
	Contact	SWGTGTLVTVSS	117 - 128	12
	IMGT	-WGTGTLVTVSS	118 - 128	11

Accession & Annotations

Accession	AAX33675.1
Source	abYsis-EMBL-IG AY789234 Submitted 26-OCT-2005 Updated 06-JAN-2006
Name	immunoglobulin heavy chain variable region
Organism	Synthetic construct
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Zhang Y.J., Wu S.Y., Wang G.J. Submitted (22-OCT-2004) to the INSDC. Fish Diseases, Hydrobiology of Institute, Luojia Shan Donghu Road, Wuhan, Hubei 430072, P.R.C. Zhang J.Y., Wang J.G., Wu Y.S., Li M., Li A.H., Gong X.L. 'A combined phage display ScFv library against Myxobolus rotundus infecting crucian carp, Carassius auratus auratus (L.), in China' J. Fish Dis. 29(1):1-7(2006).

Tools

Sequences

Amino Acid Sequence:

EVNLVQSGTVLKGPSATVQISCVTSGYSLTNYGMYWIKQFSEKSLELVAYIFTGVNYNQH
YTPKMKSKANFTKENANSSLYYMEIRNVTAEDTALYYCTWWGRSFQFLIWSLVQNPSWGT
GTLVTVSS

DNA Sequence:

gaggtcaatcttgtccagtctggcaccgttctgaaggggccttcagctactgtgcagatc
tcttgcgtcacttctggctactccctcaccaattatggcatgtactggatcaaacagttt
tctgagaagtcccttgagctggtcgcatacatatttactggcgtaaactataaccagcat
tatacccctaagatgaaatccaaagcaaattttactaaagagaacgcaaattcctccctg
tactacatggagatcagaaacgtcactgcagaggacactgccctttattactgtacctgg
tggggtcggtcttttcagtttctgatctggtccctggttcaaaacccatcatggggcacc
ggtaccctggtcaccgtctcctca

Data Source:

Alignment settings:

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