abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIQLTQSPSSLSASVGETVTLTC	1 - 23	23
CDR-L1	GASENIYGGLN	24 - 34	11
LFR2	WYQRKQGKSPQLLIY	35 - 49	15
CDR-L2	GATKLAD	50 - 56	7
LFR3	GMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	57 - 88	32
CDR-L3	QNVLSNPLT	89 - 97	9
LFR4	FGAGTKLELKRA	98 - 109	12
Tail	DAAPTVS	109 - 116	7
			116

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIQLTQSPSSLSASVGETVTLTC------	1 - 23	23
	AbM	DIQLTQSPSSLSASVGETVTLTC------	1 - 23	23
	Kabat	DIQLTQSPSSLSASVGETVTLTC------	1 - 23	23
	Contact	DIQLTQSPSSLSASVGETVTLTCGASENI	1 - 29	29
	IMGT	DIQLTQSPSSLSASVGETVTLTCGAS---	1 - 26	26
CDR-L1	Chothia	GASENIYGGLN--	24 - 34	11
	AbM	GASENIYGGLN--	24 - 34	11
	Kabat	GASENIYGGLN--	24 - 34	11
	Contact	------YGGLNWY	30 - 36	7
	IMGT	---ENIYGG----	27 - 32	6
LFR2	Chothia	--WYQRKQGKSPQLLIY	35 - 49	15
	AbM	--WYQRKQGKSPQLLIY	35 - 49	15
	Kabat	--WYQRKQGKSPQLLIY	35 - 49	15
	Contact	----QRKQGKSPQ----	37 - 45	9
	IMGT	LNWYQRKQGKSPQLLIY	33 - 49	17
CDR-L2	Chothia	----GATKLAD	50 - 56	7
	AbM	----GATKLAD	50 - 56	7
	Kabat	----GATKLAD	50 - 56	7
	Contact	LLIYGATKLA-	46 - 55	10
	IMGT	----GA-----	50 - 51	2
LFR3	Chothia	-----GMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	57 - 88	32
	AbM	-----GMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	57 - 88	32
	Kabat	-----GMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	57 - 88	32
	Contact	----DGMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	56 - 88	33
	IMGT	TKLADGMSSRFSGGGSGRQYFLKITSLHPDDVATYYC	52 - 88	37
CDR-L3	Chothia	QNVLSNPLT	89 - 97	9
	AbM	QNVLSNPLT	89 - 97	9
	Kabat	QNVLSNPLT	89 - 97	9
	Contact	QNVLSNPL-	89 - 96	8
	IMGT	QNVLSNPLT	89 - 97	9
LFR4	Chothia	-FGAGTKLELKRA	98 - 109	12
	AbM	-FGAGTKLELKRA	98 - 109	12
	Kabat	-FGAGTKLELKRA	98 - 109	12
	Contact	TFGAGTKLELKRA	97 - 109	13
	IMGT	-FGAGTKLELKRA	98 - 109	12

Accession & Annotations

Accession	ABO26564.1
Source	abYsis-EMBL-IG EF418573 Submitted 13-MAR-2007 Updated 17-NOV-2007
Name	anti-rabies glycoprotein immunoglobulin light chain variable region
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Mousli M., Turki I., Kharmachi H., Saadi M., Dellagi K. 'Recombinant single-chain Fv antibody fragment-alkaline phosphatase conjugate: a novel in vitro tool to estimate rabies viral glycoprotein antigen in vaccine manufacture' J. Virol. Methods 146(1-2):246-256(2007). Mousli M., Turki I., Kharmachi H., Dellagi K. Submitted (01-FEB-2007) to the INSDC. Immuno-biotechnology, Institut Pasteur de Tunis, 13, Place Pasteur, Tunis-Belvedere 1002, Tunisia Mousli M., Turki I., Kharmachi H., Dellagi K. 'Single chain antibody produced from PCR amplification' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DIQLTQSPSSLSASVGETVTLTCGASENIYGGLNWYQRKQGKSPQLLIYGATKLADGMSS
RFSGGGSGRQYFLKITSLHPDDVATYYCQNVLSNPLTFGAGTKLELKRADAAPTVS

DNA Sequence:

gacatccagctgactcagtctccatcttcactgtctgcatctgtgggagaaactgtcacc
ctcacatgtggagcaagtgagaatatttacggtggtttaaattggtatcagcggaaacag
ggaaaatctcctcagctcctgatctatggtgcaaccaagttggcagatggcatgtcatcg
aggttcagtggcggtggatctggtagacagtattttctcaagatcactagcctgcatcct
gacgatgttgcaacgtattactgtcaaaatgtgttaagtaatcctctcacgttcggtgct
gggaccaagctggagctgaaacgggctgatgctgcaccaactgtatcc

Data Source:

Alignment settings:

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