abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DVLMTQTPLSLPVSLGDQASISC	1 - 23	23
CDR-L1	RSSQSIVHSDGNTYLE	24 - 39	16
LFR2	WFLQKPGQSPKVLIY	40 - 54	15
CDR-L2	KVSNRFS	55 - 61	7
LFR3	GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
CDR-L3	FQGSHVPPT	94 - 102	9
LFR4	FGGGTKLEIKRA	103 - 114	12
			114

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DVLMTQTPLSLPVSLGDQASISC------	1 - 23	23
	AbM	DVLMTQTPLSLPVSLGDQASISC------	1 - 23	23
	Kabat	DVLMTQTPLSLPVSLGDQASISC------	1 - 23	23
	Contact	DVLMTQTPLSLPVSLGDQASISCRSSQSI	1 - 29	29
	IMGT	DVLMTQTPLSLPVSLGDQASISCRSS---	1 - 26	26
CDR-L1	Chothia	RSSQSIVHSDGNTYLE--	24 - 39	16
	AbM	RSSQSIVHSDGNTYLE--	24 - 39	16
	Kabat	RSSQSIVHSDGNTYLE--	24 - 39	16
	Contact	------VHSDGNTYLEWF	30 - 41	12
	IMGT	---QSIVHSDGNTY----	27 - 37	11
LFR2	Chothia	--WFLQKPGQSPKVLIY	40 - 54	15
	AbM	--WFLQKPGQSPKVLIY	40 - 54	15
	Kabat	--WFLQKPGQSPKVLIY	40 - 54	15
	Contact	----LQKPGQSPK----	42 - 50	9
	IMGT	LEWFLQKPGQSPKVLIY	38 - 54	17
CDR-L2	Chothia	----KVSNRFS	55 - 61	7
	AbM	----KVSNRFS	55 - 61	7
	Kabat	----KVSNRFS	55 - 61	7
	Contact	VLIYKVSNRF-	51 - 60	10
	IMGT	----KV-----	55 - 56	2
LFR3	Chothia	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	AbM	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	Kabat	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	Contact	----SGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	61 - 93	33
	IMGT	SNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	57 - 93	37
CDR-L3	Chothia	FQGSHVPPT	94 - 102	9
	AbM	FQGSHVPPT	94 - 102	9
	Kabat	FQGSHVPPT	94 - 102	9
	Contact	FQGSHVPP-	94 - 101	8
	IMGT	FQGSHVPPT	94 - 102	9
LFR4	Chothia	-FGGGTKLEIKRA	103 - 114	12
	AbM	-FGGGTKLEIKRA	103 - 114	12
	Kabat	-FGGGTKLEIKRA	103 - 114	12
	Contact	TFGGGTKLEIKRA	102 - 114	13
	IMGT	-FGGGTKLEIKRA	103 - 114	12

Accession & Annotations

Accession	ACK58219.1
Source	abYsis-EMBL-IG FJ477893 Submitted 24-DEC-2008 Updated 29-DEC-2008
Name	immunoglobulin light chain Fvl-cap
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Li H.J., Zhao L., Chen W. Submitted (20-NOV-2008) to the INSDC. Biotechnology, Guangdong Pharmaceutical University, Waihuan Dong Road, University Town, Guangzhou, Guangdong 510006, China Li H.J., Zhao L., Chen W. 'A single-chain variable fragment antibody against chloramphenicol' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DVLMTQTPLSLPVSLGDQASISCRSSQSIVHSDGNTYLEWFLQKPGQSPKVLIYKVSNRF
SGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCFQGSHVPPTFGGGTKLEIKRA

DNA Sequence:

gatgttttgatgacccaaactccactctccctgcctgtcagtcttggagatcaagcctcc
atctcttgcagatctagtcagagcattgttcacagtgatggaaacacctatttagaatgg
ttcctgcagaaaccaggccagtctccaaaggtcctgatctacaaagtttccaaccgcttt
tctggggtcccagacaggttcagtggcagtggatcagggacagatttcacactcaagatc
agcagagtggaggctgaggatctgggagtttatttctgctttcaaggttcacatgttcct
ccgacgttcggtggaggcaccaagctggaaatcaaacgggct

Data Source:

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