abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLKESGPGILQPSQTLSLACSFSGFSLS	1 - 30	30
CDR-H1	TFGMSVG	31 - 37	7
HFR2	WIRQSSGKGLEWLA	38 - 51	14
CDR-H2	HIWWNGVKPYNPALKS	52 - 67	16
HFR3	RLTISRDAFNNLVFLKIASVVTADSATYYCVR	68 - 99	32
CDR-H3	WSDGAMDS	100 - 107	8
HFR4	WGQGTSVTVSS	108 - 118	11
Tail	A	118 - 119	1
			119

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLKESGPGILQPSQTLSLACSFS-----	1 - 25	25
	AbM	QVQLKESGPGILQPSQTLSLACSFS-----	1 - 25	25
	Kabat	QVQLKESGPGILQPSQTLSLACSFSGFSLS	1 - 30	30
	Contact	QVQLKESGPGILQPSQTLSLACSFSGFSL-	1 - 29	29
	IMGT	QVQLKESGPGILQPSQTLSLACSFS-----	1 - 25	25
CDR-H1	Chothia	GFSLSTFGM---	26 - 34	9
	AbM	GFSLSTFGMSVG	26 - 37	12
	Kabat	-----TFGMSVG	31 - 37	7
	Contact	----STFGMSVG	30 - 37	8
	IMGT	GFSLSTFGMS--	26 - 35	10
HFR2	Chothia	SVGWIRQSSGKGLEWLAHI	35 - 53	19
	AbM	---WIRQSSGKGLEWLA--	38 - 51	14
	Kabat	---WIRQSSGKGLEWLA--	38 - 51	14
	Contact	---WIRQSSGKGLE-----	38 - 48	11
	IMGT	-VGWIRQSSGKGLEWLAH-	36 - 52	17
CDR-H2	Chothia	-----WWNGV---------	54 - 58	5
	AbM	---HIWWNGVKP-------	52 - 60	9
	Kabat	---HIWWNGVKPYNPALKS	52 - 67	16
	Contact	WLAHIWWNGVKP-------	49 - 60	12
	IMGT	----IWWNGVK--------	53 - 59	7
HFR3	Chothia	KPYNPALKSRLTISRDAFNNLVFLKIASVVTADSATYYCVR	59 - 99	41
	AbM	--YNPALKSRLTISRDAFNNLVFLKIASVVTADSATYYCVR	61 - 99	39
	Kabat	---------RLTISRDAFNNLVFLKIASVVTADSATYYCVR	68 - 99	32
	Contact	--YNPALKSRLTISRDAFNNLVFLKIASVVTADSATYYC--	61 - 97	37
	IMGT	-PYNPALKSRLTISRDAFNNLVFLKIASVVTADSATYYC--	60 - 97	38
CDR-H3	Chothia	--WSDGAMDS	100 - 107	8
	AbM	--WSDGAMDS	100 - 107	8
	Kabat	--WSDGAMDS	100 - 107	8
	Contact	VRWSDGAMD-	98 - 106	9
	IMGT	VRWSDGAMDS	98 - 107	10
HFR4	Chothia	-WGQGTSVTVSS	108 - 118	11
	AbM	-WGQGTSVTVSS	108 - 118	11
	Kabat	-WGQGTSVTVSS	108 - 118	11
	Contact	SWGQGTSVTVSS	107 - 118	12
	IMGT	-WGQGTSVTVSS	108 - 118	11

Accession & Annotations

Accession	ACK58220.1
Source	abYsis-EMBL-IG FJ477894 Submitted 24-DEC-2008 Updated 29-DEC-2008
Name	immunoglobulin heavy chain Fvh-cap
Organism	Synthetic construct
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Li H.J., Zhao L., Chen W. Submitted (20-NOV-2008) to the INSDC. Biotechnology, Guangdong Pharmaceutical University, Waihuan Dong Road, University Town, Guangzhou, Guangdong 510006, China Li H.J., Zhao L., Chen W. 'A single-chain variable fragment antibody against chloramphenicol' Unpublished.

Tools

Sequences

Amino Acid Sequence:

QVQLKESGPGILQPSQTLSLACSFSGFSLSTFGMSVGWIRQSSGKGLEWLAHIWWNGVKP
YNPALKSRLTISRDAFNNLVFLKIASVVTADSATYYCVRWSDGAMDSWGQGTSVTVSSA

DNA Sequence:

caggtgcagctgaaggagtctggccctgggatattgcagccctcccagaccctcagtctg
gcttgttctttctctgggttttcactaagcacttttggtatgagtgtaggctggattcgt
cagtcttcagggaagggtctggagtggctggcacacatttggtggaatggtgttaagccc
tataacccagccctgaaaagccgactcacaatctccagggatgctttcaacaacctggtt
ttcctcaagatcgccagtgtggtcactgctgatagtgccacatactactgtgttcgctgg
tccgatggggctatggactcctggggtcaaggaacctcagtcaccgtctcctcagcc

Data Source:

Alignment settings:

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