abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIQLTQPTSSLSASLGDRVTISC	1 - 23	23
CDR-L1	RASQDISNYLN	24 - 34	11
LFR2	WYQQKPDGTIKLLIY	35 - 49	15
CDR-L2	YTSRLHS	50 - 56	7
LFR3	GVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	57 - 88	32
CDR-L3	QQGNTLPPT	89 - 97	9
LFR4	FGGGTKLEIKR	98 - 108	11
			108

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIQLTQPTSSLSASLGDRVTISC------	1 - 23	23
	AbM	DIQLTQPTSSLSASLGDRVTISC------	1 - 23	23
	Kabat	DIQLTQPTSSLSASLGDRVTISC------	1 - 23	23
	Contact	DIQLTQPTSSLSASLGDRVTISCRASQDI	1 - 29	29
	IMGT	DIQLTQPTSSLSASLGDRVTISCRAS---	1 - 26	26
CDR-L1	Chothia	RASQDISNYLN--	24 - 34	11
	AbM	RASQDISNYLN--	24 - 34	11
	Kabat	RASQDISNYLN--	24 - 34	11
	Contact	------SNYLNWY	30 - 36	7
	IMGT	---QDISNY----	27 - 32	6
LFR2	Chothia	--WYQQKPDGTIKLLIY	35 - 49	15
	AbM	--WYQQKPDGTIKLLIY	35 - 49	15
	Kabat	--WYQQKPDGTIKLLIY	35 - 49	15
	Contact	----QQKPDGTIK----	37 - 45	9
	IMGT	LNWYQQKPDGTIKLLIY	33 - 49	17
CDR-L2	Chothia	----YTSRLHS	50 - 56	7
	AbM	----YTSRLHS	50 - 56	7
	Kabat	----YTSRLHS	50 - 56	7
	Contact	LLIYYTSRLH-	46 - 55	10
	IMGT	----YT-----	50 - 51	2
LFR3	Chothia	-----GVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	57 - 88	32
	AbM	-----GVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	57 - 88	32
	Kabat	-----GVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	57 - 88	32
	Contact	----SGVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	56 - 88	33
	IMGT	SRLHSGVPSRFSGSGSGTDYSLTISYLEQEDIATYFC	52 - 88	37
CDR-L3	Chothia	QQGNTLPPT	89 - 97	9
	AbM	QQGNTLPPT	89 - 97	9
	Kabat	QQGNTLPPT	89 - 97	9
	Contact	QQGNTLPP-	89 - 96	8
	IMGT	QQGNTLPPT	89 - 97	9
LFR4	Chothia	-FGGGTKLEIKR	98 - 108	11
	AbM	-FGGGTKLEIKR	98 - 108	11
	Kabat	-FGGGTKLEIKR	98 - 108	11
	Contact	TFGGGTKLEIKR	97 - 108	12
	IMGT	-FGGGTKLEIKR	98 - 108	11

Accession & Annotations

Accession	APU93583.1
Source	abYsis-EMBL-IG KX236314 Submitted 24-JAN-2017 Updated 24-JAN-2017
Name	anti-LMG scFv immunoglobulin light chain variable region
Clone	LMG-VL1-1
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. Submitted (10-MAY-2016) to the INSDC. Food Science, Guangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Wushan Rd, Guangzhou, Guangdong 510642, China Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. 'A universal strategy of single chain variable fragment generation for small chemicals from Hybridomas' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DIQLTQPTSSLSASLGDRVTISCRASQDISNYLNWYQQKPDGTIKLLIYYTSRLHSGVPS
RFSGSGSGTDYSLTISYLEQEDIATYFCQQGNTLPPTFGGGTKLEIKR

DNA Sequence:

gatatccagctgactcagcctacatcctccctgtctgcctctctgggagacagagtcacc
atcagttgcagggcaagtcaggacattagcaattatttaaactggtatcagcagaaacca
gatggaactattaaactcctgatctactacacatcaagattacactcaggagtcccatca
aggttcagtggcagtgggtctggaacagattattctctcaccattagctacctggaacaa
gaagatattgccacttacttttgccaacagggtaatacgcttcctccgacgttcggtgga
ggcaccaagctggaaatcaaacgt

Data Source:

Alignment settings:

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