abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIVLNQSPAIMSASPGEKVTLTC	1 - 23	23
CDR-L1	SASSSVSSSYFY	24 - 35	12
LFR2	WYQQKPGSSPKLWIY	36 - 50	15
CDR-L2	STSNLAS	51 - 57	7
LFR3	GVPARFSGSGSGTSYSLTISSMEAEDAASYFC	58 - 89	32
CDR-L3	HQWSSYPFT	90 - 98	9
LFR4	FGSGTKLEIKR	99 - 109	11
			109

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIVLNQSPAIMSASPGEKVTLTC------	1 - 23	23
	AbM	DIVLNQSPAIMSASPGEKVTLTC------	1 - 23	23
	Kabat	DIVLNQSPAIMSASPGEKVTLTC------	1 - 23	23
	Contact	DIVLNQSPAIMSASPGEKVTLTCSASSSV	1 - 29	29
	IMGT	DIVLNQSPAIMSASPGEKVTLTCSAS---	1 - 26	26
CDR-L1	Chothia	SASSSVSSSYFY--	24 - 35	12
	AbM	SASSSVSSSYFY--	24 - 35	12
	Kabat	SASSSVSSSYFY--	24 - 35	12
	Contact	------SSSYFYWY	30 - 37	8
	IMGT	---SSVSSSY----	27 - 33	7
LFR2	Chothia	--WYQQKPGSSPKLWIY	36 - 50	15
	AbM	--WYQQKPGSSPKLWIY	36 - 50	15
	Kabat	--WYQQKPGSSPKLWIY	36 - 50	15
	Contact	----QQKPGSSPK----	38 - 46	9
	IMGT	FYWYQQKPGSSPKLWIY	34 - 50	17
CDR-L2	Chothia	----STSNLAS	51 - 57	7
	AbM	----STSNLAS	51 - 57	7
	Kabat	----STSNLAS	51 - 57	7
	Contact	LWIYSTSNLA-	47 - 56	10
	IMGT	----ST-----	51 - 52	2
LFR3	Chothia	-----GVPARFSGSGSGTSYSLTISSMEAEDAASYFC	58 - 89	32
	AbM	-----GVPARFSGSGSGTSYSLTISSMEAEDAASYFC	58 - 89	32
	Kabat	-----GVPARFSGSGSGTSYSLTISSMEAEDAASYFC	58 - 89	32
	Contact	----SGVPARFSGSGSGTSYSLTISSMEAEDAASYFC	57 - 89	33
	IMGT	SNLASGVPARFSGSGSGTSYSLTISSMEAEDAASYFC	53 - 89	37
CDR-L3	Chothia	HQWSSYPFT	90 - 98	9
	AbM	HQWSSYPFT	90 - 98	9
	Kabat	HQWSSYPFT	90 - 98	9
	Contact	HQWSSYPF-	90 - 97	8
	IMGT	HQWSSYPFT	90 - 98	9
LFR4	Chothia	-FGSGTKLEIKR	99 - 109	11
	AbM	-FGSGTKLEIKR	99 - 109	11
	Kabat	-FGSGTKLEIKR	99 - 109	11
	Contact	TFGSGTKLEIKR	98 - 109	12
	IMGT	-FGSGTKLEIKR	99 - 109	11

Accession & Annotations

Accession	APU93585.1
Source	abYsis-EMBL-IG KX247680 Submitted 24-JAN-2017 Updated 24-JAN-2017
Name	anti-MG scFv immunoglobulin ligh chain variable region
Clone	MG-VL9-4
Organism	Synthetic construct
Chain Type	Light
Pairing	None
Identical Protein Sequences	None
References	Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. Submitted (13-MAY-2016) to the INSDC. Food Science, Guangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Wushan Rd, Guangzhou, Guangdong 510642, China Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. 'A universal strategy of single chain variable fragment generation for small chemicals from Hybridomas' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DIVLNQSPAIMSASPGEKVTLTCSASSSVSSSYFYWYQQKPGSSPKLWIYSTSNLASGVP
ARFSGSGSGTSYSLTISSMEAEDAASYFCHQWSSYPFTFGSGTKLEIKR

DNA Sequence:

gacattgttctcaaccagtctccagcaatcatgtctgcatctcctggggagaaggtcacc
ttgacctgcagtgccagctcaagtgtaagttccagctacttttactggtaccaacagaag
ccaggatcctcccccaaactctggatttatagcacatccaacctggcttctggagtccct
gctcgcttcagtggcagtgggtctgggacctcttactctctcacaatcagcagcatggag
gctgaagatgctgcctcttatttctgccatcagtggagtagttacccattcacgttcggc
tcggggacaaagttggaaataaaacgt

Data Source:

Alignment settings:

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