abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVKLQESGPGLVKPSQSLSLSCTVTGYSIT	1 - 30	30
CDR-H1	NDYAWN	31 - 36	6
HFR2	WIRQFPGNKLEWMG	37 - 50	14
CDR-H2	YISYSGGSSYNPSLKS	51 - 66	16
HFR3	RISITRDTSKNQFFLQLNSVTTEDTATYYCTG	67 - 98	32
CDR-H3	VITMSMDY	99 - 106	8
HFR4	WGQGTSVTVSS	107 - 117	11
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVKLQESGPGLVKPSQSLSLSCTVT-----	1 - 25	25
	AbM	DVKLQESGPGLVKPSQSLSLSCTVT-----	1 - 25	25
	Kabat	DVKLQESGPGLVKPSQSLSLSCTVTGYSIT	1 - 30	30
	Contact	DVKLQESGPGLVKPSQSLSLSCTVTGYSI-	1 - 29	29
	IMGT	DVKLQESGPGLVKPSQSLSLSCTVT-----	1 - 25	25
CDR-H1	Chothia	GYSITNDY---	26 - 33	8
	AbM	GYSITNDYAWN	26 - 36	11
	Kabat	-----NDYAWN	31 - 36	6
	Contact	----TNDYAWN	30 - 36	7
	IMGT	GYSITNDYA--	26 - 34	9
HFR2	Chothia	AWNWIRQFPGNKLEWMGYI	34 - 52	19
	AbM	---WIRQFPGNKLEWMG--	37 - 50	14
	Kabat	---WIRQFPGNKLEWMG--	37 - 50	14
	Contact	---WIRQFPGNKLE-----	37 - 47	11
	IMGT	-WNWIRQFPGNKLEWMGY-	35 - 51	17
CDR-H2	Chothia	-----SYSGG---------	53 - 57	5
	AbM	---YISYSGGSS-------	51 - 59	9
	Kabat	---YISYSGGSSYNPSLKS	51 - 66	16
	Contact	WMGYISYSGGSS-------	48 - 59	12
	IMGT	----ISYSGGS--------	52 - 58	7
HFR3	Chothia	SSYNPSLKSRISITRDTSKNQFFLQLNSVTTEDTATYYCTG	58 - 98	41
	AbM	--YNPSLKSRISITRDTSKNQFFLQLNSVTTEDTATYYCTG	60 - 98	39
	Kabat	---------RISITRDTSKNQFFLQLNSVTTEDTATYYCTG	67 - 98	32
	Contact	--YNPSLKSRISITRDTSKNQFFLQLNSVTTEDTATYYC--	60 - 96	37
	IMGT	-SYNPSLKSRISITRDTSKNQFFLQLNSVTTEDTATYYC--	59 - 96	38
CDR-H3	Chothia	--VITMSMDY	99 - 106	8
	AbM	--VITMSMDY	99 - 106	8
	Kabat	--VITMSMDY	99 - 106	8
	Contact	TGVITMSMD-	97 - 105	9
	IMGT	TGVITMSMDY	97 - 106	10
HFR4	Chothia	-WGQGTSVTVSS	107 - 117	11
	AbM	-WGQGTSVTVSS	107 - 117	11
	Kabat	-WGQGTSVTVSS	107 - 117	11
	Contact	YWGQGTSVTVSS	106 - 117	12
	IMGT	-WGQGTSVTVSS	107 - 117	11

Accession & Annotations

Accession	APU93586.1
Source	abYsis-EMBL-IG KX247681 Submitted 24-JAN-2017 Updated 24-JAN-2017
Name	anti-MG scFv immunoglobulin heavy chain variable region
Clone	MG-VH1-4
Organism	Synthetic construct
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. Submitted (13-MAY-2016) to the INSDC. Food Science, Guangdong Provincial Key Laboratory of Food Quality and Safety, South China Agricultural University, Wushan Rd, Guangzhou, Guangdong 510642, China Dong J.-X., Li Z.-F., Wang H., Sun Y.-M. 'A universal strategy of single chain variable fragment generation for small chemicals from Hybridomas' Unpublished.

Tools

Sequences

Amino Acid Sequence:

DVKLQESGPGLVKPSQSLSLSCTVTGYSITNDYAWNWIRQFPGNKLEWMGYISYSGGSSY
NPSLKSRISITRDTSKNQFFLQLNSVTTEDTATYYCTGVITMSMDYWGQGTSVTVSS

DNA Sequence:

gatgtaaagcttcaggagtcgggacctggcctggtgaaaccttctcagtctctgtccctc
tcctgcactgtcactggctactcaatcaccaatgattatgcctggaactggatccggcag
tttccaggaaacaaactggagtggatgggctacataagctacagtggtggctctagctac
aacccatctctcaaaagtcgaatctctatcactcgagacacatccaagaaccagttcttc
ctgcagttgaattctgtgactactgaggacacagccacttattactgtacaggtgtcatt
actatgtctatggactactggggtcaaggaacctcagtcaccgtctcctcg

Data Source:

Alignment settings:

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