abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLSCAASGSIFS	1 - 30	30
CDR-H1	INSMD	31 - 35	5
HFR2	WDRQAPGKQRELVA	36 - 49	14
CDR-H2	TITSGGSTNYADSVKG	50 - 65	16
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	66 - 97	32
CDR-H3	NVKTWAGMTRDY	98 - 109	12
HFR4	WGQGTQVTVSS	110 - 120	11
Tail	HHHHHH	120 - 126	6
			126

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLSCAASGSIFS	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLSCAASGSIF-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GSIFSIN---	26 - 32	7
	AbM	GSIFSINSMD	26 - 35	10
	Kabat	-----INSMD	31 - 35	5
	Contact	----SINSMD	30 - 35	6
	IMGT	GSIFSINS--	26 - 33	8
HFR2	Chothia	SMDWDRQAPGKQRELVATI	33 - 51	19
	AbM	---WDRQAPGKQRELVA--	36 - 49	14
	Kabat	---WDRQAPGKQRELVA--	36 - 49	14
	Contact	---WDRQAPGKQRE-----	36 - 46	11
	IMGT	-MDWDRQAPGKQRELVAT-	34 - 50	17
CDR-H2	Chothia	-----TSGGS---------	52 - 56	5
	AbM	---TITSGGSTN-------	50 - 58	9
	Kabat	---TITSGGSTNYADSVKG	50 - 65	16
	Contact	LVATITSGGSTN-------	47 - 58	12
	IMGT	----ITSGGST--------	51 - 57	7
HFR3	Chothia	TNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	57 - 97	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	59 - 97	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCNA	66 - 97	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	59 - 95	37
	IMGT	-NYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	58 - 95	38
CDR-H3	Chothia	--NVKTWAGMTRDY	98 - 109	12
	AbM	--NVKTWAGMTRDY	98 - 109	12
	Kabat	--NVKTWAGMTRDY	98 - 109	12
	Contact	NANVKTWAGMTRD-	96 - 108	13
	IMGT	NANVKTWAGMTRDY	96 - 109	14
HFR4	Chothia	-WGQGTQVTVSS	110 - 120	11
	AbM	-WGQGTQVTVSS	110 - 120	11
	Kabat	-WGQGTQVTVSS	110 - 120	11
	Contact	YWGQGTQVTVSS	109 - 120	12
	IMGT	-WGQGTQVTVSS	110 - 120	11

Accession & Annotations

Accession	3ezj_D
Source	PDB 3ezj Submitted 22-OCT-2008 Updated 24-JAN-2018
Name	CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE SECRETIN GSPD FROM ETEC DETERMINED WITH THE ASSISTANCE OF A NANOBODY
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 3ezj_B 3ezj_F 3ezj_H
References	KOROTKOV V., PARDON E., STEYAERT J., HOL G. 'CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE SECRETIN GSPD FROM ETEC DETERMINED WITH THE ASSISTANCE OF A NANOBODY.' STRUCTURE V. 17 255 2009 ISSN 0969-2126

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLSCAASGSIFSINSMDWDRQAPGKQRELVATITSGGSTNYA
DSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNANVKTWAGMTRDYWGQGTQVTVSS
HHHHHH