abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	MA	1 - 2	2
HFR1	DVQLQESGGGSVQAGGSLRLSCAASGDTFS	3 - 32	30
CDR-H1	SYSMA	33 - 37	5
HFR2	WFRQAPGKECELVS	38 - 51	14
CDR-H2	NILRDGTTTYAGSVKG	52 - 67	16
HFR3	RFTISRDDAKNTVYLQMVNLKSEDTARYYCAA	68 - 99	32
CDR-H3	DSGTQLGYVGAVGLSCLDYVMDY	100 - 122	23
HFR4	WGKGTQVTVSS	123 - 133	11
Tail	HHHHHH	133 - 139	6
			139

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLQESGGGSVQAGGSLRLSCAAS-----	3 - 27	25
	AbM	DVQLQESGGGSVQAGGSLRLSCAAS-----	3 - 27	25
	Kabat	DVQLQESGGGSVQAGGSLRLSCAASGDTFS	3 - 32	30
	Contact	DVQLQESGGGSVQAGGSLRLSCAASGDTF-	3 - 31	29
	IMGT	DVQLQESGGGSVQAGGSLRLSCAAS-----	3 - 27	25
CDR-H1	Chothia	GDTFSSY---	28 - 34	7
	AbM	GDTFSSYSMA	28 - 37	10
	Kabat	-----SYSMA	33 - 37	5
	Contact	----SSYSMA	32 - 37	6
	IMGT	GDTFSSYS--	28 - 35	8
HFR2	Chothia	SMAWFRQAPGKECELVSNI	35 - 53	19
	AbM	---WFRQAPGKECELVS--	38 - 51	14
	Kabat	---WFRQAPGKECELVS--	38 - 51	14
	Contact	---WFRQAPGKECE-----	38 - 48	11
	IMGT	-MAWFRQAPGKECELVSN-	36 - 52	17
CDR-H2	Chothia	-----LRDGT---------	54 - 58	5
	AbM	---NILRDGTTT-------	52 - 60	9
	Kabat	---NILRDGTTTYAGSVKG	52 - 67	16
	Contact	LVSNILRDGTTT-------	49 - 60	12
	IMGT	----ILRDGTT--------	53 - 59	7
HFR3	Chothia	TTYAGSVKGRFTISRDDAKNTVYLQMVNLKSEDTARYYCAA	59 - 99	41
	AbM	--YAGSVKGRFTISRDDAKNTVYLQMVNLKSEDTARYYCAA	61 - 99	39
	Kabat	---------RFTISRDDAKNTVYLQMVNLKSEDTARYYCAA	68 - 99	32
	Contact	--YAGSVKGRFTISRDDAKNTVYLQMVNLKSEDTARYYC--	61 - 97	37
	IMGT	-TYAGSVKGRFTISRDDAKNTVYLQMVNLKSEDTARYYC--	60 - 97	38
CDR-H3	Chothia	--DSGTQLGYVGAVGLSCLDYVMDY	100 - 122	23
	AbM	--DSGTQLGYVGAVGLSCLDYVMDY	100 - 122	23
	Kabat	--DSGTQLGYVGAVGLSCLDYVMDY	100 - 122	23
	Contact	AADSGTQLGYVGAVGLSCLDYVMD-	98 - 121	24
	IMGT	AADSGTQLGYVGAVGLSCLDYVMDY	98 - 122	25
HFR4	Chothia	-WGKGTQVTVSS	123 - 133	11
	AbM	-WGKGTQVTVSS	123 - 133	11
	Kabat	-WGKGTQVTVSS	123 - 133	11
	Contact	YWGKGTQVTVSS	122 - 133	12
	IMGT	-WGKGTQVTVSS	123 - 133	11

Accession & Annotations

Accession	3g9a_B
Source	PDB 3g9a Submitted 13-FEB-2009 Updated 18-SEP-2013
Name	GREEN FLUORESCENT PROTEIN BOUND TO MINIMIZER NANOBODY
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	KIRCHHOFER A., HELMA J., SCHMIDTHALS K., FRAUER C., CUI S., KARCHER A., PELLIS M., MUYLDERMANS S., DEULCCI C., CARDOSO C., LEONHARDT H., HOPFNER -P., ROTHBAUER U. 'MODULATION OF PROTEIN PROPERTIES IN LIVING CELLS USING NANOBODIES' NAT.STRUCT.MOL.BIOL. V. 17 133 2010 ISSN 1545-9993

Tools

Sequences

Amino Acid Sequence:

MADVQLQESGGGSVQAGGSLRLSCAASGDTFSSYSMAWFRQAPGKECELVSNILRDGTTT
YAGSVKGRFTISRDDAKNTVYLQMVNLKSEDTARYYCAADSGTQLGYVGAVGLSCLDYVM
DYWGKGTQVTVSSHHHHHH