abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQTGGSLRLSCAASEYTQS	1 - 30	30
CDR-H1	SACMG	31 - 35	5
HFR2	WFRQAPGKEREGVA	36 - 49	14
CDR-H2	GISRFFGTAYYADSVKG	50 - 66	17
HFR3	RFTISQDKAKNTVYLQMNSLKPEDTAIYYCAA	67 - 98	32
CDR-H3	GQGCLTTIQALGGAYGYNA	99 - 117	19
HFR4	WGQGTQVTVSS	118 - 128	11
Tail	HHHHHH	128 - 134	6
			134

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQTGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQTGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQTGGSLRLSCAASEYTQS	1 - 30	30
	Contact	QVQLQESGGGSVQTGGSLRLSCAASEYTQ-	1 - 29	29
	IMGT	QVQLQESGGGSVQTGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	EYTQSSA---	26 - 32	7
	AbM	EYTQSSACMG	26 - 35	10
	Kabat	-----SACMG	31 - 35	5
	Contact	----SSACMG	30 - 35	6
	IMGT	EYTQSSAC--	26 - 33	8
HFR2	Chothia	CMGWFRQAPGKEREGVAGI	33 - 51	19
	AbM	---WFRQAPGKEREGVA--	36 - 49	14
	Kabat	---WFRQAPGKEREGVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREGVAG-	34 - 50	17
CDR-H2	Chothia	-----SRFFGT---------	52 - 57	6
	AbM	---GISRFFGTAY-------	50 - 59	10
	Kabat	---GISRFFGTAYYADSVKG	50 - 66	17
	Contact	GVAGISRFFGTAY-------	47 - 59	13
	IMGT	----ISRFFGTA--------	51 - 58	8
HFR3	Chothia	AYYADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYCAA	58 - 98	41
	AbM	--YADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYCAA	60 - 98	39
	Kabat	---------RFTISQDKAKNTVYLQMNSLKPEDTAIYYCAA	67 - 98	32
	Contact	--YADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYC--	60 - 96	37
	IMGT	-YYADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYC--	59 - 96	38
CDR-H3	Chothia	--GQGCLTTIQALGGAYGYNA	99 - 117	19
	AbM	--GQGCLTTIQALGGAYGYNA	99 - 117	19
	Kabat	--GQGCLTTIQALGGAYGYNA	99 - 117	19
	Contact	AAGQGCLTTIQALGGAYGYN-	97 - 116	20
	IMGT	AAGQGCLTTIQALGGAYGYNA	97 - 117	21
HFR4	Chothia	-WGQGTQVTVSS	118 - 128	11
	AbM	-WGQGTQVTVSS	118 - 128	11
	Kabat	-WGQGTQVTVSS	118 - 128	11
	Contact	AWGQGTQVTVSS	117 - 128	12
	IMGT	-WGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	3jbc_7
Source	PDB 3jbc Submitted 26-AUG-2015 Updated 18-JUL-2018
Name	COMPLEX OF POLIOVIRUS WITH VHH PVSP29F
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	STRAUSS M., SCHOTTE L., THYS B., FILMAN J., HOGLE M. 'FIVE OF FIVE VHHS NEUTRALIZING POLIOVIRUS BIND THE RECEPTOR-BINDING SITE.' J.VIROL. V. 90 3496 2016 ISSN 0022-538X

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQTGGSLRLSCAASEYTQSSACMGWFRQAPGKEREGVAGISRFFGTAYY
ADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYCAAGQGCLTTIQALGGAYGYNAWGQ
GTQVTVSSHHHHHH