abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCAASGYQYS	1 - 30	30
CDR-H1	LLCMA	31 - 35	5
HFR2	WFRQVLGEGREGVA	36 - 49	14
CDR-H2	FITTYNGAMRYADTVKG	50 - 66	17
HFR3	RFTVSQDKDKNTVYLQMNSLKPEDTAIYYCAA	67 - 98	32
CDR-H3	GRWRFGDICHEGSGYNY	99 - 115	17
HFR4	WGQGTQVTVSS	116 - 126	11
Tail	HHHHHH	126 - 132	6
			132

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCAASGYQYS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCAASGYQY-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GYQYSLL---	26 - 32	7
	AbM	GYQYSLLCMA	26 - 35	10
	Kabat	-----LLCMA	31 - 35	5
	Contact	----SLLCMA	30 - 35	6
	IMGT	GYQYSLLC--	26 - 33	8
HFR2	Chothia	CMAWFRQVLGEGREGVAFI	33 - 51	19
	AbM	---WFRQVLGEGREGVA--	36 - 49	14
	Kabat	---WFRQVLGEGREGVA--	36 - 49	14
	Contact	---WFRQVLGEGRE-----	36 - 46	11
	IMGT	-MAWFRQVLGEGREGVAF-	34 - 50	17
CDR-H2	Chothia	-----TTYNGA---------	52 - 57	6
	AbM	---FITTYNGAMR-------	50 - 59	10
	Kabat	---FITTYNGAMRYADTVKG	50 - 66	17
	Contact	GVAFITTYNGAMR-------	47 - 59	13
	IMGT	----ITTYNGAM--------	51 - 58	8
HFR3	Chothia	MRYADTVKGRFTVSQDKDKNTVYLQMNSLKPEDTAIYYCAA	58 - 98	41
	AbM	--YADTVKGRFTVSQDKDKNTVYLQMNSLKPEDTAIYYCAA	60 - 98	39
	Kabat	---------RFTVSQDKDKNTVYLQMNSLKPEDTAIYYCAA	67 - 98	32
	Contact	--YADTVKGRFTVSQDKDKNTVYLQMNSLKPEDTAIYYC--	60 - 96	37
	IMGT	-RYADTVKGRFTVSQDKDKNTVYLQMNSLKPEDTAIYYC--	59 - 96	38
CDR-H3	Chothia	--GRWRFGDICHEGSGYNY	99 - 115	17
	AbM	--GRWRFGDICHEGSGYNY	99 - 115	17
	Kabat	--GRWRFGDICHEGSGYNY	99 - 115	17
	Contact	AAGRWRFGDICHEGSGYN-	97 - 114	18
	IMGT	AAGRWRFGDICHEGSGYNY	97 - 115	19
HFR4	Chothia	-WGQGTQVTVSS	116 - 126	11
	AbM	-WGQGTQVTVSS	116 - 126	11
	Kabat	-WGQGTQVTVSS	116 - 126	11
	Contact	YWGQGTQVTVSS	115 - 126	12
	IMGT	-WGQGTQVTVSS	116 - 126	11

Accession & Annotations

Accession	3jbe_7
Source	PDB 3jbe Submitted 26-AUG-2015 Updated 18-JUL-2018
Name	COMPLEX OF POLIOVIRUS WITH VHH PVSS8A
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	STRAUSS M., SCHOTTE L., THYS B., FILMAN J., HOGLE M. 'FIVE OF FIVE VHHS NEUTRALIZING POLIOVIRUS BIND THE RECEPTOR-BINDING SITE.' J.VIROL. V. 90 3496 2016 ISSN 0022-538X

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCAASGYQYSLLCMAWFRQVLGEGREGVAFITTYNGAMRY
ADTVKGRFTVSQDKDKNTVYLQMNSLKPEDTAIYYCAAGRWRFGDICHEGSGYNYWGQGT
QVTVSSHHHHHH