abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGSVQAGGSLRLSCAASEYIPS	1 - 30	30
CDR-H1	ANCMR	31 - 35	5
HFR2	WFRQAPKEREWVA	36 - 48	13
CDR-H2	SVLRGGYTWHADSVKG	49 - 64	16
HFR3	RFTISGDNAKTAAYLQMNSLKPEDTAIYYCAY	65 - 96	32
CDR-H3	SNTCPGASADFRS	97 - 109	13
HFR4	WGQGTQVTVSS	110 - 120	11
Tail	HHHHHH	120 - 126	6
			126

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGSVQAGGSLRLSCAASEYIPS	1 - 30	30
	Contact	QVQLQESGGGSVQAGGSLRLSCAASEYIP-	1 - 29	29
	IMGT	QVQLQESGGGSVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	EYIPSAN---	26 - 32	7
	AbM	EYIPSANCMR	26 - 35	10
	Kabat	-----ANCMR	31 - 35	5
	Contact	----SANCMR	30 - 35	6
	IMGT	EYIPSANC--	26 - 33	8
HFR2	Chothia	CMRWFRQAPKEREWVASV	33 - 50	18
	AbM	---WFRQAPKEREWVA--	36 - 48	13
	Kabat	---WFRQAPKEREWVA--	36 - 48	13
	Contact	---WFRQAPKERE-----	36 - 45	10
	IMGT	-MRWFRQAPKEREWVAS-	34 - 49	16
CDR-H2	Chothia	-----LRGGY---------	51 - 55	5
	AbM	---SVLRGGYTW-------	49 - 57	9
	Kabat	---SVLRGGYTWHADSVKG	49 - 64	16
	Contact	WVASVLRGGYTW-------	46 - 57	12
	IMGT	----VLRGGYT--------	50 - 56	7
HFR3	Chothia	TWHADSVKGRFTISGDNAKTAAYLQMNSLKPEDTAIYYCAY	56 - 96	41
	AbM	--HADSVKGRFTISGDNAKTAAYLQMNSLKPEDTAIYYCAY	58 - 96	39
	Kabat	---------RFTISGDNAKTAAYLQMNSLKPEDTAIYYCAY	65 - 96	32
	Contact	--HADSVKGRFTISGDNAKTAAYLQMNSLKPEDTAIYYC--	58 - 94	37
	IMGT	-WHADSVKGRFTISGDNAKTAAYLQMNSLKPEDTAIYYC--	57 - 94	38
CDR-H3	Chothia	--SNTCPGASADFRS	97 - 109	13
	AbM	--SNTCPGASADFRS	97 - 109	13
	Kabat	--SNTCPGASADFRS	97 - 109	13
	Contact	AYSNTCPGASADFR-	95 - 108	14
	IMGT	AYSNTCPGASADFRS	95 - 109	15
HFR4	Chothia	-WGQGTQVTVSS	110 - 120	11
	AbM	-WGQGTQVTVSS	110 - 120	11
	Kabat	-WGQGTQVTVSS	110 - 120	11
	Contact	SWGQGTQVTVSS	109 - 120	12
	IMGT	-WGQGTQVTVSS	110 - 120	11

Accession & Annotations

Accession	3jbg_7
Source	PDB 3jbg Submitted 26-AUG-2015 Updated 18-JUL-2018
Name	COMPLEX OF POLIOVIRUS WITH VHH PVSS21E
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	STRAUSS M., SCHOTTE L., THYS B., FILMAN J., HOGLE M. 'FIVE OF FIVE VHHS NEUTRALIZING POLIOVIRUS BIND THE RECEPTOR-BINDING SITE.' J.VIROL. V. 90 3496 2016 ISSN 0022-538X

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGSVQAGGSLRLSCAASEYIPSANCMRWFRQAPKEREWVASVLRGGYTWHAD
SVKGRFTISGDNAKTAAYLQMNSLKPEDTAIYYCAYSNTCPGASADFRSWGQGTQVTVSS
HHHHHH