abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	MA	1 - 2	2
HFR1	QVQLVESGGALVQPGGSLRLSCAASGFPVN	3 - 32	30
CDR-H1	RYSMR	33 - 37	5
HFR2	WYRQAPGKEREWVA	38 - 51	14
CDR-H2	GMSSAGDRSSYEDSVKG	52 - 68	17
HFR3	RFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	69 - 100	32
CDR-H3	NVGFEY	101 - 106	6
HFR4	WGQGTQVTVSS	107 - 117	11
Tail	HHHHHH	117 - 123	6
			123

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLVESGGALVQPGGSLRLSCAAS-----	3 - 27	25
	AbM	QVQLVESGGALVQPGGSLRLSCAAS-----	3 - 27	25
	Kabat	QVQLVESGGALVQPGGSLRLSCAASGFPVN	3 - 32	30
	Contact	QVQLVESGGALVQPGGSLRLSCAASGFPV-	3 - 31	29
	IMGT	QVQLVESGGALVQPGGSLRLSCAAS-----	3 - 27	25
CDR-H1	Chothia	GFPVNRY---	28 - 34	7
	AbM	GFPVNRYSMR	28 - 37	10
	Kabat	-----RYSMR	33 - 37	5
	Contact	----NRYSMR	32 - 37	6
	IMGT	GFPVNRYS--	28 - 35	8
HFR2	Chothia	SMRWYRQAPGKEREWVAGM	35 - 53	19
	AbM	---WYRQAPGKEREWVA--	38 - 51	14
	Kabat	---WYRQAPGKEREWVA--	38 - 51	14
	Contact	---WYRQAPGKERE-----	38 - 48	11
	IMGT	-MRWYRQAPGKEREWVAG-	36 - 52	17
CDR-H2	Chothia	-----SSAGDR---------	54 - 59	6
	AbM	---GMSSAGDRSS-------	52 - 61	10
	Kabat	---GMSSAGDRSSYEDSVKG	52 - 68	17
	Contact	WVAGMSSAGDRSS-------	49 - 61	13
	IMGT	----MSSAGDRS--------	53 - 60	8
HFR3	Chothia	SSYEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	60 - 100	41
	AbM	--YEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	62 - 100	39
	Kabat	---------RFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	69 - 100	32
	Contact	--YEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYC--	62 - 98	37
	IMGT	-SYEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYC--	61 - 98	38
CDR-H3	Chothia	--NVGFEY	101 - 106	6
	AbM	--NVGFEY	101 - 106	6
	Kabat	--NVGFEY	101 - 106	6
	Contact	NVNVGFE-	99 - 105	7
	IMGT	NVNVGFEY	99 - 106	8
HFR4	Chothia	-WGQGTQVTVSS	107 - 117	11
	AbM	-WGQGTQVTVSS	107 - 117	11
	Kabat	-WGQGTQVTVSS	107 - 117	11
	Contact	YWGQGTQVTVSS	106 - 117	12
	IMGT	-WGQGTQVTVSS	107 - 117	11

Accession & Annotations

Accession	3k1k_C
Source	PDB 3k1k Submitted 28-SEP-2009 Updated 25-JAN-2017
Name	GREEN FLUORESCENT PROTEIN BOUND TO ENHANCER NANOBODY
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 3k1k_D
References	KIRCHHOFER A., HELMA J., SCHMIDTHALS K., FRAUER C., CUI S., KARCHER A., PELLIS M., MUYLDERMANS S., DEULCCI C., CARDOSO C., LEONHARDT H., HOPFNER -P., ROTHBAUER U. 'MODULATION OF PROTEIN PROPERTIES IN LIVING CELLS USING NANOBODIES' NAT.STRUCT.MOL.BIOL. V. 17 133 2010 ISSN 1545-9993

Tools

Sequences

Amino Acid Sequence:

MAQVQLVESGGALVQPGGSLRLSCAASGFPVNRYSMRWYRQAPGKEREWVAGMSSAGDRS
SYEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNVNVGFEYWGQGTQVTVSSHHH
HHH