abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	M	1 - 1	1
HFR1	QVQLVESGGALVQPGGSLRLSCAASGFPVN	2 - 31	30
CDR-H1	RYSMR	32 - 36	5
HFR2	WYRQAPGKEREWVA	37 - 50	14
CDR-H2	GMSSAGDRSSYEDSVKG	51 - 67	17
HFR3	RFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	68 - 99	32
CDR-H3	NVGFEY	100 - 105	6
HFR4	WGQGTQVTVSS	106 - 116	11
Tail	KHHHHHH	116 - 123	7
			123

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLVESGGALVQPGGSLRLSCAAS-----	2 - 26	25
	AbM	QVQLVESGGALVQPGGSLRLSCAAS-----	2 - 26	25
	Kabat	QVQLVESGGALVQPGGSLRLSCAASGFPVN	2 - 31	30
	Contact	QVQLVESGGALVQPGGSLRLSCAASGFPV-	2 - 30	29
	IMGT	QVQLVESGGALVQPGGSLRLSCAAS-----	2 - 26	25
CDR-H1	Chothia	GFPVNRY---	27 - 33	7
	AbM	GFPVNRYSMR	27 - 36	10
	Kabat	-----RYSMR	32 - 36	5
	Contact	----NRYSMR	31 - 36	6
	IMGT	GFPVNRYS--	27 - 34	8
HFR2	Chothia	SMRWYRQAPGKEREWVAGM	34 - 52	19
	AbM	---WYRQAPGKEREWVA--	37 - 50	14
	Kabat	---WYRQAPGKEREWVA--	37 - 50	14
	Contact	---WYRQAPGKERE-----	37 - 47	11
	IMGT	-MRWYRQAPGKEREWVAG-	35 - 51	17
CDR-H2	Chothia	-----SSAGDR---------	53 - 58	6
	AbM	---GMSSAGDRSS-------	51 - 60	10
	Kabat	---GMSSAGDRSSYEDSVKG	51 - 67	17
	Contact	WVAGMSSAGDRSS-------	48 - 60	13
	IMGT	----MSSAGDRS--------	52 - 59	8
HFR3	Chothia	SSYEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	59 - 99	41
	AbM	--YEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	61 - 99	39
	Kabat	---------RFTISRDDARNTVYLQMNSLKPEDTAVYYCNV	68 - 99	32
	Contact	--YEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYC--	61 - 97	37
	IMGT	-SYEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYC--	60 - 97	38
CDR-H3	Chothia	--NVGFEY	100 - 105	6
	AbM	--NVGFEY	100 - 105	6
	Kabat	--NVGFEY	100 - 105	6
	Contact	NVNVGFE-	98 - 104	7
	IMGT	NVNVGFEY	98 - 105	8
HFR4	Chothia	-WGQGTQVTVSS	106 - 116	11
	AbM	-WGQGTQVTVSS	106 - 116	11
	Kabat	-WGQGTQVTVSS	106 - 116	11
	Contact	YWGQGTQVTVSS	105 - 116	12
	IMGT	-WGQGTQVTVSS	106 - 116	11

Accession & Annotations

Accession	3ogo_H
Source	PDB 3ogo Submitted 17-AUG-2010 Updated 12-JAN-2011
Name	STRUCTURE OF THE GFP:GFP-NANOBODY COMPLEX AT 2.8 A RESOLUTION IN SPACEGROUP P21212
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 3ogo_E 3ogo_F 3ogo_G
References	KUBALA H., KOVTUN O., ALEXANDROV K., COLLINS M. 'STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE GFP:GFP-NANOBODY COMPLEX.' PROTEIN SCI. V. 19 2389 2010 ISSN 0961-8368

Tools

Sequences

Amino Acid Sequence:

MQVQLVESGGALVQPGGSLRLSCAASGFPVNRYSMRWYRQAPGKEREWVAGMSSAGDRSS
YEDSVKGRFTISRDDARNTVYLQMNSLKPEDTAVYYCNVNVGFEYWGQGTQVTVSSKHHH
HHH