abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLSCAASGRTLS	1 - 30	30
CDR-H1	SYAMG	31 - 35	5
HFR2	WFRQAPGKEREFVA	36 - 49	14
CDR-H2	AINRSGSTFYADAVKG	50 - 65	16
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAAYYCAA	66 - 97	32
CDR-H3	DRFSPVVPGPIPVNTVDS	98 - 115	18
HFR4	WGQGTQVTVSS	116 - 126	11
Tail	HHHHHH	126 - 132	6
			132

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLSCAASGRTLS	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLSCAASGRTL-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GRTLSSY---	26 - 32	7
	AbM	GRTLSSYAMG	26 - 35	10
	Kabat	-----SYAMG	31 - 35	5
	Contact	----SSYAMG	30 - 35	6
	IMGT	GRTLSSYA--	26 - 33	8
HFR2	Chothia	AMGWFRQAPGKEREFVAAI	33 - 51	19
	AbM	---WFRQAPGKEREFVA--	36 - 49	14
	Kabat	---WFRQAPGKEREFVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREFVAA-	34 - 50	17
CDR-H2	Chothia	-----NRSGS---------	52 - 56	5
	AbM	---AINRSGSTF-------	50 - 58	9
	Kabat	---AINRSGSTFYADAVKG	50 - 65	16
	Contact	FVAAINRSGSTF-------	47 - 58	12
	IMGT	----INRSGST--------	51 - 57	7
HFR3	Chothia	TFYADAVKGRFTISRDNAKNTVYLQMNSLKPEDTAAYYCAA	57 - 97	41
	AbM	--YADAVKGRFTISRDNAKNTVYLQMNSLKPEDTAAYYCAA	59 - 97	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAAYYCAA	66 - 97	32
	Contact	--YADAVKGRFTISRDNAKNTVYLQMNSLKPEDTAAYYC--	59 - 95	37
	IMGT	-FYADAVKGRFTISRDNAKNTVYLQMNSLKPEDTAAYYC--	58 - 95	38
CDR-H3	Chothia	--DRFSPVVPGPIPVNTVDS	98 - 115	18
	AbM	--DRFSPVVPGPIPVNTVDS	98 - 115	18
	Kabat	--DRFSPVVPGPIPVNTVDS	98 - 115	18
	Contact	AADRFSPVVPGPIPVNTVD-	96 - 114	19
	IMGT	AADRFSPVVPGPIPVNTVDS	96 - 115	20
HFR4	Chothia	-WGQGTQVTVSS	116 - 126	11
	AbM	-WGQGTQVTVSS	116 - 126	11
	Kabat	-WGQGTQVTVSS	116 - 126	11
	Contact	SWGQGTQVTVSS	115 - 126	12
	IMGT	-WGQGTQVTVSS	116 - 126	11

Accession & Annotations

Accession	3stb_A
Source	PDB 3stb Submitted 09-JUL-2011 Updated 18-SEP-2013
Name	A COMPLEX OF TWO EDITOSOME PROTEINS AND TWO NANOBODIES
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 3stb_B
References	PARK J., PARDON E., WU M., STEYAERT J., HOL G. 'CRYSTAL STRUCTURE OF A HETERODIMER OF EDITOSOME INTERACTION PROTEINS IN COMPLEX WITH TWO COPIES OF A CROSS-REACTING NANOBODY.' NUCLEIC ACIDS RES. V. 40 1828 2012 ISSN 0305-1048

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLSCAASGRTLSSYAMGWFRQAPGKEREFVAAINRSGSTFYA
DAVKGRFTISRDNAKNTVYLQMNSLKPEDTAAYYCAADRFSPVVPGPIPVNTVDSWGQGT
QVTVSSHHHHHH