abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	EVQLVQSGGGVVQPGRSLRLSCSSSGFIFS	1 - 30	30
CDR-H1	SYAMY	31 - 35	5
HFR2	WVRQAPGKGLEWVA	36 - 49	14
CDR-H2	IIWDDGSDQHYADSVKG	50 - 66	17
HFR3	RFTISRNDSKNTLFLQMDSLRPEDTGVYFCAR	67 - 98	32
CDR-H3	DGGHGFCSSASCFGPDY	99 - 115	17
HFR4	WGQGTPVTVSS	116 - 126	11
Tail	ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPQPVTVSWNSGALTSGVHTFPAVLQSS GLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGG PSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPQVKFNWYVDGVQVHNAKTKPREQQYN STYRVVSVLTVLHQNWLDGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREE MTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRW QQGNVFSCSVMHEALHNHYTQKSLSLSPG	126 - 455	329
			455

Accession & Annotations

Accession	2ig2_H
Source	PDB 2ig2 Submitted 18-APR-1989 Updated 24-FEB-2009
Name	DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L- KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)
Organism	Homo sapiens
Human Subgroup	Heavy chain subgroup III
Chain Type	Heavy
Pairing	2ig2_L
Identical Protein Sequences	None
References	KRATZIN D., PALM W., STANGEL M., SCHMIDT E., FRIEDRICH J., HILSCHMANN N. 'THE PRIMARY STRUCTURE OF CRYSTALLIZABLE MONOCLONAL IMMUNOGLOBULIN IGG1 KOL. II. AMINO ACID SEQUENCE OF THE L-CHAIN, GAMMA-TYPE, SUBGROUP I' BIOL.CHEM.HOPPE-SEYLER V. 370 263 1989 ISSN 0177-3593

Tools

Sequences

Amino Acid Sequence:

EVQLVQSGGGVVQPGRSLRLSCSSSGFIFSSYAMYWVRQAPGKGLEWVAIIWDDGSDQHY
ADSVKGRFTISRNDSKNTLFLQMDSLRPEDTGVYFCARDGGHGFCSSASCFGPDYWGQGT
PVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPQPVTVSWNSGALTSGVHTFP
AVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPA
PELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPQVKFNWYVDGVQVHNAKTKP
REQQYNSTYRVVSVLTVLHQNWLDGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTL
PPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLT
VDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

Data Source:

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