abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLSCAASGRTSS	1 - 30	30
CDR-H1	LYSMG	31 - 35	5
HFR2	WFRQAPGKEREFVA	36 - 49	14
CDR-H2	AISRNGANTYYTDSVKG	50 - 66	17
HFR3	RFTISRDNAKNTVELQMNSLKPEDTAVYYCAA	67 - 98	32
CDR-H3	DRFPTMEVVTIMTNEYDY	99 - 116	18
HFR4	WGQGTQVTVSS	117 - 127	11
Tail	HHHHHH	127 - 133	6
			133

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLSCAASGRTSS	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLSCAASGRTS-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GRTSSLY---	26 - 32	7
	AbM	GRTSSLYSMG	26 - 35	10
	Kabat	-----LYSMG	31 - 35	5
	Contact	----SLYSMG	30 - 35	6
	IMGT	GRTSSLYS--	26 - 33	8
HFR2	Chothia	SMGWFRQAPGKEREFVAAI	33 - 51	19
	AbM	---WFRQAPGKEREFVA--	36 - 49	14
	Kabat	---WFRQAPGKEREFVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREFVAA-	34 - 50	17
CDR-H2	Chothia	-----SRNGAN---------	52 - 57	6
	AbM	---AISRNGANTY-------	50 - 59	10
	Kabat	---AISRNGANTYYTDSVKG	50 - 66	17
	Contact	FVAAISRNGANTY-------	47 - 59	13
	IMGT	----ISRNGANT--------	51 - 58	8
HFR3	Chothia	TYYTDSVKGRFTISRDNAKNTVELQMNSLKPEDTAVYYCAA	58 - 98	41
	AbM	--YTDSVKGRFTISRDNAKNTVELQMNSLKPEDTAVYYCAA	60 - 98	39
	Kabat	---------RFTISRDNAKNTVELQMNSLKPEDTAVYYCAA	67 - 98	32
	Contact	--YTDSVKGRFTISRDNAKNTVELQMNSLKPEDTAVYYC--	60 - 96	37
	IMGT	-YYTDSVKGRFTISRDNAKNTVELQMNSLKPEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--DRFPTMEVVTIMTNEYDY	99 - 116	18
	AbM	--DRFPTMEVVTIMTNEYDY	99 - 116	18
	Kabat	--DRFPTMEVVTIMTNEYDY	99 - 116	18
	Contact	AADRFPTMEVVTIMTNEYD-	97 - 115	19
	IMGT	AADRFPTMEVVTIMTNEYDY	97 - 116	20
HFR4	Chothia	-WGQGTQVTVSS	117 - 127	11
	AbM	-WGQGTQVTVSS	117 - 127	11
	Kabat	-WGQGTQVTVSS	117 - 127	11
	Contact	YWGQGTQVTVSS	116 - 127	12
	IMGT	-WGQGTQVTVSS	117 - 127	11

Accession & Annotations

Accession	4dk3_B
Source	PDB 4dk3 Submitted 03-FEB-2012 Updated 15-NOV-2017
Name	STRUCTURE OF EDITOSOME PROTEIN
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 4dk3_A 4dk6_A 4dk6_B
References	PARK J., BUDIARTO T., WU M., PARDON E., STEYAERT J., HOL G. 'THE STRUCTURE OF THE C-TERMINAL DOMAIN OF THE LARGEST EDITOSOME INTERACTION PROTEIN AND ITS ROLE IN PROMOTING RNA BINDING BY RNA-EDITING LIGASE L2.' NUCLEIC ACIDS RES. V. 40 6966 2012 ISSN 0305-1048

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLSCAASGRTSSLYSMGWFRQAPGKEREFVAAISRNGANTYY
TDSVKGRFTISRDNAKNTVELQMNSLKPEDTAVYYCAADRFPTMEVVTIMTNEYDYWGQG
TQVTVSSHHHHHH