abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLVESGGGLVQPGGSLRLSCAYSGSLFS	1 - 30	30
CDR-H1	ILRMD	31 - 35	5
HFR2	WYRQAPGKERELVA	36 - 49	14
CDR-H2	GITRDAAGYADSTNYADSVKG	50 - 70	21
HFR3	RFTISRDSAKNTVYLQMNSLKPEDTAVYYCNA	71 - 102	32
CDR-H3	DARTITGRADY	103 - 113	11
HFR4	WGQGTQVTVSS	114 - 124	11
			124

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLVESGGGLVQPGGSLRLSCAYS-----	1 - 25	25
	AbM	DVQLVESGGGLVQPGGSLRLSCAYS-----	1 - 25	25
	Kabat	DVQLVESGGGLVQPGGSLRLSCAYSGSLFS	1 - 30	30
	Contact	DVQLVESGGGLVQPGGSLRLSCAYSGSLF-	1 - 29	29
	IMGT	DVQLVESGGGLVQPGGSLRLSCAYS-----	1 - 25	25
CDR-H1	Chothia	GSLFSIL---	26 - 32	7
	AbM	GSLFSILRMD	26 - 35	10
	Kabat	-----ILRMD	31 - 35	5
	Contact	----SILRMD	30 - 35	6
	IMGT	GSLFSILR--	26 - 33	8
HFR2	Chothia	RMDWYRQAPGKERELVAGI	33 - 51	19
	AbM	---WYRQAPGKERELVA--	36 - 49	14
	Kabat	---WYRQAPGKERELVA--	36 - 49	14
	Contact	---WYRQAPGKERE-----	36 - 46	11
	IMGT	-MDWYRQAPGKERELVAG-	34 - 50	17
CDR-H2	Chothia	-----TRDAAGYADS---------	52 - 61	10
	AbM	---GITRDAAGYADSTN-------	50 - 63	14
	Kabat	---GITRDAAGYADSTNYADSVKG	50 - 70	21
	Contact	LVAGITRDAAGYADSTN-------	47 - 63	17
	IMGT	----ITRDAAGYADST--------	51 - 62	12
HFR3	Chothia	TNYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCNA	62 - 102	41
	AbM	--YADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCNA	64 - 102	39
	Kabat	---------RFTISRDSAKNTVYLQMNSLKPEDTAVYYCNA	71 - 102	32
	Contact	--YADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYC--	64 - 100	37
	IMGT	-NYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYC--	63 - 100	38
CDR-H3	Chothia	--DARTITGRADY	103 - 113	11
	AbM	--DARTITGRADY	103 - 113	11
	Kabat	--DARTITGRADY	103 - 113	11
	Contact	NADARTITGRAD-	101 - 112	12
	IMGT	NADARTITGRADY	101 - 113	13
HFR4	Chothia	-WGQGTQVTVSS	114 - 124	11
	AbM	-WGQGTQVTVSS	114 - 124	11
	Kabat	-WGQGTQVTVSS	114 - 124	11
	Contact	YWGQGTQVTVSS	113 - 124	12
	IMGT	-WGQGTQVTVSS	114 - 124	11

Accession & Annotations

Accession	4pir_J
Source	PDB 4pir Submitted 09-MAY-2014 Updated 17-SEP-2014
Name	X-RAY STRUCTURE OF THE MOUSE SEROTONIN 5-HT3 RECEPTOR
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 4pir_F 4pir_G 4pir_H 4pir_I
References	HASSAINE G., DELUZ C., GRASSO L., WYSS R., TOL B., HOVIUS R., GRAFF A., STAHLBERG H., TOMIZAKI T., DESMYTER A., MOREAU C., LI D., POITEVIN F., VOGEL H., NURY H. 'X-RAY STRUCTURE OF THE MOUSE SEROTONIN 5-HT3 RECEPTOR.' NATURE V. 512 276 2014 ESSN 1476-4687

Tools

Sequences

Amino Acid Sequence:

DVQLVESGGGLVQPGGSLRLSCAYSGSLFSILRMDWYRQAPGKERELVAGITRDAAGYAD
STNYADSVKGRFTISRDSAKNTVYLQMNSLKPEDTAVYYCNADARTITGRADYWGQGTQV
TVSS