abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLSCAASGSTFG	1 - 30	30
CDR-H1	IRTMG	31 - 35	5
HFR2	WYRQAPGKQRDLVA	36 - 49	14
CDR-H2	IISSGGSTDYADSVKG	50 - 65	16
HFR3	RFTISRDNAKNTVYLQMDSLKPEDTAIYYCNA	66 - 97	32
CDR-H3	RVGITMLAH	98 - 106	9
HFR4	WGQGTQVTVSS	107 - 117	11
			117

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLSCAASGSTFG	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLSCAASGSTF-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GSTFGIR---	26 - 32	7
	AbM	GSTFGIRTMG	26 - 35	10
	Kabat	-----IRTMG	31 - 35	5
	Contact	----GIRTMG	30 - 35	6
	IMGT	GSTFGIRT--	26 - 33	8
HFR2	Chothia	TMGWYRQAPGKQRDLVAII	33 - 51	19
	AbM	---WYRQAPGKQRDLVA--	36 - 49	14
	Kabat	---WYRQAPGKQRDLVA--	36 - 49	14
	Contact	---WYRQAPGKQRD-----	36 - 46	11
	IMGT	-MGWYRQAPGKQRDLVAI-	34 - 50	17
CDR-H2	Chothia	-----SSGGS---------	52 - 56	5
	AbM	---IISSGGSTD-------	50 - 58	9
	Kabat	---IISSGGSTDYADSVKG	50 - 65	16
	Contact	LVAIISSGGSTD-------	47 - 58	12
	IMGT	----ISSGGST--------	51 - 57	7
HFR3	Chothia	TDYADSVKGRFTISRDNAKNTVYLQMDSLKPEDTAIYYCNA	57 - 97	41
	AbM	--YADSVKGRFTISRDNAKNTVYLQMDSLKPEDTAIYYCNA	59 - 97	39
	Kabat	---------RFTISRDNAKNTVYLQMDSLKPEDTAIYYCNA	66 - 97	32
	Contact	--YADSVKGRFTISRDNAKNTVYLQMDSLKPEDTAIYYC--	59 - 95	37
	IMGT	-DYADSVKGRFTISRDNAKNTVYLQMDSLKPEDTAIYYC--	58 - 95	38
CDR-H3	Chothia	--RVGITMLAH	98 - 106	9
	AbM	--RVGITMLAH	98 - 106	9
	Kabat	--RVGITMLAH	98 - 106	9
	Contact	NARVGITMLA-	96 - 105	10
	IMGT	NARVGITMLAH	96 - 106	11
HFR4	Chothia	-WGQGTQVTVSS	107 - 117	11
	AbM	-WGQGTQVTVSS	107 - 117	11
	Kabat	-WGQGTQVTVSS	107 - 117	11
	Contact	HWGQGTQVTVSS	106 - 117	12
	IMGT	-WGQGTQVTVSS	107 - 117	11

Accession & Annotations

Accession	4zg1_F
Source	PDB 4zg1 Submitted 22-APR-2015 Updated 17-JAN-2018
Name	CRYSTAL STRUCTURE OF A NANOBODY RAISED AGAINST KDM5B
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 4zg1_A 4zg1_B 4zg1_C 4zg1_D 4zg1_E
References	WIUF A., KRISTENSEN H., KRISTENSEN O., DOROSZ J., JENSEN J., GAJHEDE M. 'STRUCTURE AND BINDING PROPERTIES OF A CAMELOID NANOBODY RAISED AGAINST KDM5B.' ACTA CRYSTALLOGR.,SECT.F V. 71 1235 2015 ESSN 2053-230X

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLSCAASGSTFGIRTMGWYRQAPGKQRDLVAIISSGGSTDYA
DSVKGRFTISRDNAKNTVYLQMDSLKPEDTAIYYCNARVGITMLAHWGQGTQVTVSS