abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
Leader	AGTGSG	1 - 6	6
HFR1	QVQLQESGGGLVQPGGSLRLSCVVSGDY	7 - 34	28
CDR-H1	YAIG	35 - 38	4
HFR2	WFRQAPGKEREGVA	39 - 52	14
CDR-H2	AISSRDGSTYYPDAVKG	53 - 69	17
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	70 - 101	32
CDR-H3	DRRQRWGPYYYLSALEYVY	102 - 120	19
HFR4	WGQGTQVTVSS	121 - 131	11
			131

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCVVS---	7 - 31	25
	AbM	QVQLQESGGGLVQPGGSLRLSCVVS---	7 - 31	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCVVSGDY	7 - 34	28
	Contact	QVQLQESGGGLVQPGGSLRLSCVVSGDY	7 - 34	28
	IMGT	QVQLQESGGGLVQPGGSLRLSCVVS---	7 - 31	25
CDR-H1	Chothia	GDYY---	32 - 35	4
	AbM	GDYYAIG	32 - 38	7
	Kabat	---YAIG	35 - 38	4
	Contact	---YAIG	35 - 38	4
	IMGT	GDYYA--	32 - 36	5
HFR2	Chothia	AIGWFRQAPGKEREGVAAI	36 - 54	19
	AbM	---WFRQAPGKEREGVA--	39 - 52	14
	Kabat	---WFRQAPGKEREGVA--	39 - 52	14
	Contact	---WFRQAPGKERE-----	39 - 49	11
	IMGT	-IGWFRQAPGKEREGVAA-	37 - 53	17
CDR-H2	Chothia	-----SSRDGS---------	55 - 60	6
	AbM	---AISSRDGSTY-------	53 - 62	10
	Kabat	---AISSRDGSTYYPDAVKG	53 - 69	17
	Contact	GVAAISSRDGSTY-------	50 - 62	13
	IMGT	----ISSRDGST--------	54 - 61	8
HFR3	Chothia	TYYPDAVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	61 - 101	41
	AbM	--YPDAVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	63 - 101	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYYCAA	70 - 101	32
	Contact	--YPDAVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	63 - 99	37
	IMGT	-YYPDAVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYC--	62 - 99	38
CDR-H3	Chothia	--DRRQRWGPYYYLSALEYVY	102 - 120	19
	AbM	--DRRQRWGPYYYLSALEYVY	102 - 120	19
	Kabat	--DRRQRWGPYYYLSALEYVY	102 - 120	19
	Contact	AADRRQRWGPYYYLSALEYV-	100 - 119	20
	IMGT	AADRRQRWGPYYYLSALEYVY	100 - 120	21
HFR4	Chothia	-WGQGTQVTVSS	121 - 131	11
	AbM	-WGQGTQVTVSS	121 - 131	11
	Kabat	-WGQGTQVTVSS	121 - 131	11
	Contact	YWGQGTQVTVSS	120 - 131	12
	IMGT	-WGQGTQVTVSS	121 - 131	11

Accession & Annotations

Accession	5c2u_B
Source	PDB 5c2u Submitted 16-JUN-2015 Updated 14-OCT-2015
Name	FERREDOXIN-LIKE DOMAIN OF NUCLEOPORIN NUP54 BOUND TO A NANOBODY
Organism	Camelus dromedarius
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	CHUG H., TRAKHANOV S., HULSMANN B., PLEINER T., GORLICH D. 'CRYSTAL STRUCTURE OF THE METAZOAN NUP62NUP58NUP54 NUCLEOPORIN COMPLEX.' SCIENCE V. 350 106 2015 ESSN 1095-9203

Tools

Sequences

Amino Acid Sequence:

AGTGSGQVQLQESGGGLVQPGGSLRLSCVVSGDYYAIGWFRQAPGKEREGVAAISSRDGS
TYYPDAVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAADRRQRWGPYYYLSALEYVY
WGQGTQVTVSS