abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLQESGGGLVQAGGSLRLSCTGSGRTFR	1 - 30	30
CDR-H1	NYPMA	31 - 35	5
HFR2	WFRQAPGKEREFVA	36 - 49	14
CDR-H2	GITWVGASTLYADFAKG	50 - 66	17
HFR3	RFTISRDNAKNTVYLQMNSLKPEDTAVYSCAA	67 - 98	32
CDR-H3	GRGIVAGRIPAEYAD	99 - 113	15
HFR4	WGQGTQVTVSS	114 - 124	11
Tail	EPKTPKPQPAAAHHHHHHGAAEQKLISEEDLNGAA	124 - 159	35
			159

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLQESGGGLVQAGGSLRLSCTGS-----	1 - 25	25
	AbM	DVQLQESGGGLVQAGGSLRLSCTGS-----	1 - 25	25
	Kabat	DVQLQESGGGLVQAGGSLRLSCTGSGRTFR	1 - 30	30
	Contact	DVQLQESGGGLVQAGGSLRLSCTGSGRTF-	1 - 29	29
	IMGT	DVQLQESGGGLVQAGGSLRLSCTGS-----	1 - 25	25
CDR-H1	Chothia	GRTFRNY---	26 - 32	7
	AbM	GRTFRNYPMA	26 - 35	10
	Kabat	-----NYPMA	31 - 35	5
	Contact	----RNYPMA	30 - 35	6
	IMGT	GRTFRNYP--	26 - 33	8
HFR2	Chothia	PMAWFRQAPGKEREFVAGI	33 - 51	19
	AbM	---WFRQAPGKEREFVA--	36 - 49	14
	Kabat	---WFRQAPGKEREFVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MAWFRQAPGKEREFVAG-	34 - 50	17
CDR-H2	Chothia	-----TWVGAS---------	52 - 57	6
	AbM	---GITWVGASTL-------	50 - 59	10
	Kabat	---GITWVGASTLYADFAKG	50 - 66	17
	Contact	FVAGITWVGASTL-------	47 - 59	13
	IMGT	----ITWVGAST--------	51 - 58	8
HFR3	Chothia	TLYADFAKGRFTISRDNAKNTVYLQMNSLKPEDTAVYSCAA	58 - 98	41
	AbM	--YADFAKGRFTISRDNAKNTVYLQMNSLKPEDTAVYSCAA	60 - 98	39
	Kabat	---------RFTISRDNAKNTVYLQMNSLKPEDTAVYSCAA	67 - 98	32
	Contact	--YADFAKGRFTISRDNAKNTVYLQMNSLKPEDTAVYSC--	60 - 96	37
	IMGT	-LYADFAKGRFTISRDNAKNTVYLQMNSLKPEDTAVYSC--	59 - 96	38
CDR-H3	Chothia	--GRGIVAGRIPAEYAD	99 - 113	15
	AbM	--GRGIVAGRIPAEYAD	99 - 113	15
	Kabat	--GRGIVAGRIPAEYAD	99 - 113	15
	Contact	AAGRGIVAGRIPAEYA-	97 - 112	16
	IMGT	AAGRGIVAGRIPAEYAD	97 - 113	17
HFR4	Chothia	-WGQGTQVTVSS	114 - 124	11
	AbM	-WGQGTQVTVSS	114 - 124	11
	Kabat	-WGQGTQVTVSS	114 - 124	11
	Contact	DWGQGTQVTVSS	113 - 124	12
	IMGT	-WGQGTQVTVSS	114 - 124	11

Accession & Annotations

Accession	5f1k_C
Source	PDB 5f1k Submitted 30-NOV-2015 Updated 15-JUN-2016
Name	HUMAN CD38 IN COMPLEX WITH NANOBODY MU1053
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5f1k_D
References	LI T., QI S., UNGER M., HOU N., DENG W., LIU J., LAM M., WANG W., XIN D., ZHANG P., KOCH-NOLTE F., HAO Q., ZHANG H., LEE C., ZHAO J. 'IMMUNO-TARGETING THE MULTIFUNCTIONAL CD38 USING NANOBODY' SCI REP V. 6 27055 2016 ESSN 2045-2322

Tools

Sequences

Amino Acid Sequence:

DVQLQESGGGLVQAGGSLRLSCTGSGRTFRNYPMAWFRQAPGKEREFVAGITWVGASTLY
ADFAKGRFTISRDNAKNTVYLQMNSLKPEDTAVYSCAAGRGIVAGRIPAEYADWGQGTQV
TVSSEPKTPKPQPAAAHHHHHHGAAEQKLISEEDLNGAA

Data Source:

Alignment settings:

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