abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	DVQLQESGGGLVQAGHSLRLSCVGSGSRFD	1 - 30	30
CDR-H1	NYAMG	31 - 35	5
HFR2	WFRQAPGKEREFVA	36 - 49	14
CDR-H2	AISWSSGTTRYLDTVKG	50 - 66	17
HFR3	RFTISRDNAKSTVYLQMNSLKPEDTAVYYCAA	67 - 98	32
CDR-H3	RYQPRYYDSGDMDGYEYDN	99 - 117	19
HFR4	WGQGTQVTVSS	118 - 128	11
Tail	EPKTPKPQPAAAHHHHHHGAAEQKLISEEDLNGAA	128 - 163	35
			163

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	DVQLQESGGGLVQAGHSLRLSCVGS-----	1 - 25	25
	AbM	DVQLQESGGGLVQAGHSLRLSCVGS-----	1 - 25	25
	Kabat	DVQLQESGGGLVQAGHSLRLSCVGSGSRFD	1 - 30	30
	Contact	DVQLQESGGGLVQAGHSLRLSCVGSGSRF-	1 - 29	29
	IMGT	DVQLQESGGGLVQAGHSLRLSCVGS-----	1 - 25	25
CDR-H1	Chothia	GSRFDNY---	26 - 32	7
	AbM	GSRFDNYAMG	26 - 35	10
	Kabat	-----NYAMG	31 - 35	5
	Contact	----DNYAMG	30 - 35	6
	IMGT	GSRFDNYA--	26 - 33	8
HFR2	Chothia	AMGWFRQAPGKEREFVAAI	33 - 51	19
	AbM	---WFRQAPGKEREFVA--	36 - 49	14
	Kabat	---WFRQAPGKEREFVA--	36 - 49	14
	Contact	---WFRQAPGKERE-----	36 - 46	11
	IMGT	-MGWFRQAPGKEREFVAA-	34 - 50	17
CDR-H2	Chothia	-----SWSSGT---------	52 - 57	6
	AbM	---AISWSSGTTR-------	50 - 59	10
	Kabat	---AISWSSGTTRYLDTVKG	50 - 66	17
	Contact	FVAAISWSSGTTR-------	47 - 59	13
	IMGT	----ISWSSGTT--------	51 - 58	8
HFR3	Chothia	TRYLDTVKGRFTISRDNAKSTVYLQMNSLKPEDTAVYYCAA	58 - 98	41
	AbM	--YLDTVKGRFTISRDNAKSTVYLQMNSLKPEDTAVYYCAA	60 - 98	39
	Kabat	---------RFTISRDNAKSTVYLQMNSLKPEDTAVYYCAA	67 - 98	32
	Contact	--YLDTVKGRFTISRDNAKSTVYLQMNSLKPEDTAVYYC--	60 - 96	37
	IMGT	-RYLDTVKGRFTISRDNAKSTVYLQMNSLKPEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--RYQPRYYDSGDMDGYEYDN	99 - 117	19
	AbM	--RYQPRYYDSGDMDGYEYDN	99 - 117	19
	Kabat	--RYQPRYYDSGDMDGYEYDN	99 - 117	19
	Contact	AARYQPRYYDSGDMDGYEYD-	97 - 116	20
	IMGT	AARYQPRYYDSGDMDGYEYDN	97 - 117	21
HFR4	Chothia	-WGQGTQVTVSS	118 - 128	11
	AbM	-WGQGTQVTVSS	118 - 128	11
	Kabat	-WGQGTQVTVSS	118 - 128	11
	Contact	NWGQGTQVTVSS	117 - 128	12
	IMGT	-WGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	5f1o_B
Source	PDB 5f1o Submitted 30-NOV-2015 Updated 15-JUN-2016
Name	HUMAN CD38 IN COMPLEX WITH NANOBODY MU551
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	None
References	LI T., QI S., UNGER M., HOU N., DENG W., LIU J., LAM M., WANG W., XIN D., ZHANG P., KOCH-NOLTE F., HAO Q., ZHANG H., LEE C., ZHAO J. 'IMMUNO-TARGETING THE MULTIFUNCTIONAL CD38 USING NANOBODY' SCI REP V. 6 27055 2016 ESSN 2045-2322

Tools

Sequences

Amino Acid Sequence:

DVQLQESGGGLVQAGHSLRLSCVGSGSRFDNYAMGWFRQAPGKEREFVAAISWSSGTTRY
LDTVKGRFTISRDNAKSTVYLQMNSLKPEDTAVYYCAARYQPRYYDSGDMDGYEYDNWGQ
GTQVTVSSEPKTPKPQPAAAHHHHHHGAAEQKLISEEDLNGAA

Data Source:

Alignment settings:

Search settings: