abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQAGGSLRLSCTASVNIIG	1 - 30	30
CDR-H1	GNHWA	31 - 35	5
HFR2	WYRQAPGQQRDLVA	36 - 49	14
CDR-H2	SLSRYNANYADSVKG	50 - 64	15
HFR3	RFTISRDNAKNAAYLQMNSLKPEDTAIYFCAL	65 - 96	32
CDR-H3	ENYY	97 - 100	4
HFR4	WGQGTQVTVSS	101 - 111	11
Tail	HHHHHHEPEA	111 - 121	10
			121

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQAGGSLRLSCTASVNIIG	1 - 30	30
	Contact	QVQLQESGGGLVQAGGSLRLSCTASVNII-	1 - 29	29
	IMGT	QVQLQESGGGLVQAGGSLRLSCTAS-----	1 - 25	25
CDR-H1	Chothia	VNIIGGN---	26 - 32	7
	AbM	VNIIGGNHWA	26 - 35	10
	Kabat	-----GNHWA	31 - 35	5
	Contact	----GGNHWA	30 - 35	6
	IMGT	VNIIGGNH--	26 - 33	8
HFR2	Chothia	HWAWYRQAPGQQRDLVASL	33 - 51	19
	AbM	---WYRQAPGQQRDLVA--	36 - 49	14
	Kabat	---WYRQAPGQQRDLVA--	36 - 49	14
	Contact	---WYRQAPGQQRD-----	36 - 46	11
	IMGT	-WAWYRQAPGQQRDLVAS-	34 - 50	17
CDR-H2	Chothia	-----SRYN---------	52 - 55	4
	AbM	---SLSRYNAN-------	50 - 57	8
	Kabat	---SLSRYNANYADSVKG	50 - 64	15
	Contact	LVASLSRYNAN-------	47 - 57	11
	IMGT	----LSRYNA--------	51 - 56	6
HFR3	Chothia	ANYADSVKGRFTISRDNAKNAAYLQMNSLKPEDTAIYFCAL	56 - 96	41
	AbM	--YADSVKGRFTISRDNAKNAAYLQMNSLKPEDTAIYFCAL	58 - 96	39
	Kabat	---------RFTISRDNAKNAAYLQMNSLKPEDTAIYFCAL	65 - 96	32
	Contact	--YADSVKGRFTISRDNAKNAAYLQMNSLKPEDTAIYFC--	58 - 94	37
	IMGT	-NYADSVKGRFTISRDNAKNAAYLQMNSLKPEDTAIYFC--	57 - 94	38
CDR-H3	Chothia	--ENYY	97 - 100	4
	AbM	--ENYY	97 - 100	4
	Kabat	--ENYY	97 - 100	4
	Contact	ALENY-	95 - 99	5
	IMGT	ALENYY	95 - 100	6
HFR4	Chothia	-WGQGTQVTVSS	101 - 111	11
	AbM	-WGQGTQVTVSS	101 - 111	11
	Kabat	-WGQGTQVTVSS	101 - 111	11
	Contact	YWGQGTQVTVSS	100 - 111	12
	IMGT	-WGQGTQVTVSS	101 - 111	11

Accession & Annotations

Accession	5ip4_B
Source	PDB 5ip4 Submitted 09-MAR-2016 Updated 10-AUG-2016
Name	X-RAY STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5ip4_A
References	BURGER D., STIHLE M., SHARMA A., DI LELLO P., BENZ J., D'ARCY B., DEBULPAEP M., FRY D., HUBER W., KREMER T., LAEREMANS T., MATILE H., ROSS A., RUFER C., SCHOCH G., STEINMETZ O., STEYAERT J., RUDOLPH G., THOMA R., RUF A. 'CRYSTAL STRUCTURES OF THE HUMAN DOUBLECORTIN C- AND N-TERMINAL DOMAINS IN COMPLEX WITH SPECIFIC ANTIBODIES.' J.BIOL.CHEM. V. 291 16292 2016 ESSN 1083-351X

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQAGGSLRLSCTASVNIIGGNHWAWYRQAPGQQRDLVASLSRYNANYAD
SVKGRFTISRDNAKNAAYLQMNSLKPEDTAIYFCALENYYWGQGTQVTVSSHHHHHHEPE
A