abYsis

Numbering & Regions

Comparison Organism:

Calculating, please wait ...

Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQAGDALTLSCAASGRSVD	1 - 27	27
CDR-H1	NYAMG	28 - 32	5
HFR2	WFRQAPGKELEFVA	33 - 46	14
CDR-H2	AISWWSGSRTEYADSVKG	47 - 64	18
HFR3	RFTISRDNANGMVYLRMSSLRPEDTAVYYCAA	65 - 96	32
CDR-H3	ERGTYFAGRSQDEYDD	97 - 112	16
HFR4	WGRGTQVT	113 - 120	8
			120

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQAGDALTLSCAAS-----	1 - 22	22
	AbM	LQESGGGLVQAGDALTLSCAAS-----	1 - 22	22
	Kabat	LQESGGGLVQAGDALTLSCAASGRSVD	1 - 27	27
	Contact	LQESGGGLVQAGDALTLSCAASGRSV-	1 - 26	26
	IMGT	LQESGGGLVQAGDALTLSCAAS-----	1 - 22	22
CDR-H1	Chothia	GRSVDNY---	23 - 29	7
	AbM	GRSVDNYAMG	23 - 32	10
	Kabat	-----NYAMG	28 - 32	5
	Contact	----DNYAMG	27 - 32	6
	IMGT	GRSVDNYA--	23 - 30	8
HFR2	Chothia	AMGWFRQAPGKELEFVAAI	30 - 48	19
	AbM	---WFRQAPGKELEFVA--	33 - 46	14
	Kabat	---WFRQAPGKELEFVA--	33 - 46	14
	Contact	---WFRQAPGKELE-----	33 - 43	11
	IMGT	-MGWFRQAPGKELEFVAA-	31 - 47	17
CDR-H2	Chothia	-----SWWSGSR---------	49 - 55	7
	AbM	---AISWWSGSRTE-------	47 - 57	11
	Kabat	---AISWWSGSRTEYADSVKG	47 - 64	18
	Contact	FVAAISWWSGSRTE-------	44 - 57	14
	IMGT	----ISWWSGSRT--------	48 - 56	9
HFR3	Chothia	TEYADSVKGRFTISRDNANGMVYLRMSSLRPEDTAVYYCAA	56 - 96	41
	AbM	--YADSVKGRFTISRDNANGMVYLRMSSLRPEDTAVYYCAA	58 - 96	39
	Kabat	---------RFTISRDNANGMVYLRMSSLRPEDTAVYYCAA	65 - 96	32
	Contact	--YADSVKGRFTISRDNANGMVYLRMSSLRPEDTAVYYC--	58 - 94	37
	IMGT	-EYADSVKGRFTISRDNANGMVYLRMSSLRPEDTAVYYC--	57 - 94	38
CDR-H3	Chothia	--ERGTYFAGRSQDEYDD	97 - 112	16
	AbM	--ERGTYFAGRSQDEYDD	97 - 112	16
	Kabat	--ERGTYFAGRSQDEYDD	97 - 112	16
	Contact	AAERGTYFAGRSQDEYD-	95 - 111	17
	IMGT	AAERGTYFAGRSQDEYDD	95 - 112	18
HFR4	Chothia	-WGRGTQVT	113 - 120	8
	AbM	-WGRGTQVT	113 - 120	8
	Kabat	-WGRGTQVT	113 - 120	8
	Contact	DWGRGTQVT	112 - 120	9
	IMGT	-WGRGTQVT	113 - 120	8

Accession & Annotations

Accession	CAH18860.1
Source	abYsis-EMBL-IG AJ811564 Submitted 20-AUG-2004 Updated 13-OCT-2004
Name	immunoglobulin heavy chain variable region
Clone	M210
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	abYsis-EMBL-IG: CAJ55287.1
References	Harmsen M.M. Submitted (19-AUG-2004) to the INSDC. Harmsen M.M., Infection Biology, Animal Sciences Group (ID-Lelystad BV), Edelhertweg 15, Lelystad, 8219 PH, NETHERLANDS. Harmsen M.M., Van Solt C.B., Van Keulen L. 'Selection of llama single-domain antibody fragments binding to recombinant bovine prion protein in ELISA' Unpublished.

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQAGDALTLSCAASGRSVDNYAMGWFRQAPGKELEFVAAISWWSGSRTEYAD
SVKGRFTISRDNANGMVYLRMSSLRPEDTAVYYCAAERGTYFAGRSQDEYDDWGRGTQVT

DNA Sequence:

ctgcaggagtcagggggaggattggtgcaggctggggacgctctgacactctcctgtgca
gcctctggacgctcggtcgataactatgccatgggctggttccgccaggctccagggaag
gagctcgagtttgtagcggctattagctggtggagtggtagtaggacagagtatgcagac
tccgtgaagggccgattcaccatctccagagacaacgccaacggcatggtgtatttgcga
atgagcagcctccgacctgaggacacggccgtttattactgtgcagctgagcgtggtact
tacttcgccgggagatcccaagatgagtatgacgactggggccgggggacccaggtcacc

Data Source:

Alignment settings:

Search settings: