abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIVMTQSPASLAVSLGQRAIISC	1 - 23	23
CDR-L1	RASQSVSTSTSNYMH	24 - 38	15
LFR2	WYQQKPGHPPRPLIR	39 - 53	15
CDR-L2	FASNLAS	54 - 60	7
LFR3	GVPARFSGSGSGADFTLNIHPVEEEDIATYFC	61 - 92	32
CDR-L3	QHSWEIPFT	93 - 101	9
LFR4	FGGGTKLG	102 - 109	8
			109

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIVMTQSPASLAVSLGQRAIISC------	1 - 23	23
	AbM	DIVMTQSPASLAVSLGQRAIISC------	1 - 23	23
	Kabat	DIVMTQSPASLAVSLGQRAIISC------	1 - 23	23
	Contact	DIVMTQSPASLAVSLGQRAIISCRASQSV	1 - 29	29
	IMGT	DIVMTQSPASLAVSLGQRAIISCRAS---	1 - 26	26
CDR-L1	Chothia	RASQSVSTSTSNYMH--	24 - 38	15
	AbM	RASQSVSTSTSNYMH--	24 - 38	15
	Kabat	RASQSVSTSTSNYMH--	24 - 38	15
	Contact	------STSTSNYMHWY	30 - 40	11
	IMGT	---QSVSTSTSNY----	27 - 36	10
LFR2	Chothia	--WYQQKPGHPPRPLIR	39 - 53	15
	AbM	--WYQQKPGHPPRPLIR	39 - 53	15
	Kabat	--WYQQKPGHPPRPLIR	39 - 53	15
	Contact	----QQKPGHPPR----	41 - 49	9
	IMGT	MHWYQQKPGHPPRPLIR	37 - 53	17
CDR-L2	Chothia	----FASNLAS	54 - 60	7
	AbM	----FASNLAS	54 - 60	7
	Kabat	----FASNLAS	54 - 60	7
	Contact	PLIRFASNLA-	50 - 59	10
	IMGT	----FA-----	54 - 55	2
LFR3	Chothia	-----GVPARFSGSGSGADFTLNIHPVEEEDIATYFC	61 - 92	32
	AbM	-----GVPARFSGSGSGADFTLNIHPVEEEDIATYFC	61 - 92	32
	Kabat	-----GVPARFSGSGSGADFTLNIHPVEEEDIATYFC	61 - 92	32
	Contact	----SGVPARFSGSGSGADFTLNIHPVEEEDIATYFC	60 - 92	33
	IMGT	SNLASGVPARFSGSGSGADFTLNIHPVEEEDIATYFC	56 - 92	37
CDR-L3	Chothia	QHSWEIPFT	93 - 101	9
	AbM	QHSWEIPFT	93 - 101	9
	Kabat	QHSWEIPFT	93 - 101	9
	Contact	QHSWEIPF-	93 - 100	8
	IMGT	QHSWEIPFT	93 - 101	9
LFR4	Chothia	-FGGGTKLG	102 - 109	8
	AbM	-FGGGTKLG	102 - 109	8
	Kabat	-FGGGTKLG	102 - 109	8
	Contact	TFGGGTKLG	101 - 109	9
	IMGT	-FGGGTKLG	102 - 109	8

Accession & Annotations

Accession	AAG49021.1
Source	abYsis-EMBL-IG AY008762 Submitted 18-JAN-2001 Updated 09-OCT-2001
Name	anti-human C3a receptor single-chain variable fragment antibody light chain
Clone	E6
Organism	Synthetic construct
Chain Type	Light
Pairing	AAG49020.1
Identical Protein Sequences	None
References	Hawlisch H. Submitted (05-OCT-2000) to the INSDC. Medical Microbiology, Medical School Hannover, Carl-Neuberg-Str.1, Hannover, NDS 30625, Germany Hawlisch H., Muller M., Frank R., Bautsch W., Klos A., Kohl J. 'Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets' Anal. Biochem. 293(1):142-145(2001).

Tools

Sequences

Amino Acid Sequence:

DIVMTQSPASLAVSLGQRAIISCRASQSVSTSTSNYMHWYQQKPGHPPRPLIRFASNLAS
GVPARFSGSGSGADFTLNIHPVEEEDIATYFCQHSWEIPFTFGGGTKLG

DNA Sequence:

gacattgtgatgacccagtctcctgcttccttagctgtatctctggggcagagggccatc
atctcatgcagggccagccaaagtgtcagtacttctacctctaattatatgcactggtac
caacagaaaccaggacacccacccagacccctcatcaggtttgcatccaacctagcatct
ggggtccctgccaggttcagtggcagtgggtctggggcagacttcaccctcaacatccat
cctgtggaggaggaggatatagcaacatatttctgtcagcacagttgggagattccgttc
acgttcggaggggggaccaagctggg

Data Source:

Alignment settings:

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