abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	VQLQQSGAELVEPGASVKLSCKTSGYTFT	1 - 29	29
CDR-H1	SYWMH	30 - 34	5
HFR2	WVKQRPGQGLEWIG	35 - 48	14
CDR-H2	EINPTNGCTSYNEKFKS	49 - 65	17
HFR3	KATLTVDKSSSTAYMQLSSLTSEDSAVYYCAT	66 - 97	32
CDR-H3	DY	98 - 99	2
HFR4	WGQGTTLTVSS	100 - 110	11
Tail	G	110 - 111	1
			111

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	VQLQQSGAELVEPGASVKLSCKTS-----	1 - 24	24
	AbM	VQLQQSGAELVEPGASVKLSCKTS-----	1 - 24	24
	Kabat	VQLQQSGAELVEPGASVKLSCKTSGYTFT	1 - 29	29
	Contact	VQLQQSGAELVEPGASVKLSCKTSGYTF-	1 - 28	28
	IMGT	VQLQQSGAELVEPGASVKLSCKTS-----	1 - 24	24
CDR-H1	Chothia	GYTFTSY---	25 - 31	7
	AbM	GYTFTSYWMH	25 - 34	10
	Kabat	-----SYWMH	30 - 34	5
	Contact	----TSYWMH	29 - 34	6
	IMGT	GYTFTSYW--	25 - 32	8
HFR2	Chothia	WMHWVKQRPGQGLEWIGEI	32 - 50	19
	AbM	---WVKQRPGQGLEWIG--	35 - 48	14
	Kabat	---WVKQRPGQGLEWIG--	35 - 48	14
	Contact	---WVKQRPGQGLE-----	35 - 45	11
	IMGT	-MHWVKQRPGQGLEWIGE-	33 - 49	17
CDR-H2	Chothia	-----NPTNGC---------	51 - 56	6
	AbM	---EINPTNGCTS-------	49 - 58	10
	Kabat	---EINPTNGCTSYNEKFKS	49 - 65	17
	Contact	WIGEINPTNGCTS-------	46 - 58	13
	IMGT	----INPTNGCT--------	50 - 57	8
HFR3	Chothia	TSYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYCAT	57 - 97	41
	AbM	--YNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYCAT	59 - 97	39
	Kabat	---------KATLTVDKSSSTAYMQLSSLTSEDSAVYYCAT	66 - 97	32
	Contact	--YNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYC--	59 - 95	37
	IMGT	-SYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYC--	58 - 95	38
CDR-H3	Chothia	--DY	98 - 99	2
	AbM	--DY	98 - 99	2
	Kabat	--DY	98 - 99	2
	Contact	ATD-	96 - 98	3
	IMGT	ATDY	96 - 99	4
HFR4	Chothia	-WGQGTTLTVSS	100 - 110	11
	AbM	-WGQGTTLTVSS	100 - 110	11
	Kabat	-WGQGTTLTVSS	100 - 110	11
	Contact	YWGQGTTLTVSS	99 - 110	12
	IMGT	-WGQGTTLTVSS	100 - 110	11

Accession & Annotations

Accession	AAG49020.1
Source	abYsis-EMBL-IG AY008761 Submitted 18-JAN-2001 Updated 09-OCT-2001
Name	anti-human C3a receptor single-chain variable fragment antibody heavy chain
Clone	E6
Organism	Synthetic construct
Chain Type	Heavy
Pairing	AAG49021.1
Identical Protein Sequences	None
References	Hawlisch H. Submitted (05-OCT-2000) to the INSDC. Medical Microbiology, Medical School Hannover, Carl-Neuberg-Str.1, Hannover, NDS 30625, Germany Hawlisch H., Muller M., Frank R., Bautsch W., Klos A., Kohl J. 'Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets' Anal. Biochem. 293(1):142-145(2001).

Tools

Sequences

Amino Acid Sequence:

VQLQQSGAELVEPGASVKLSCKTSGYTFTSYWMHWVKQRPGQGLEWIGEINPTNGCTSYN
EKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYYCATDYWGQGTTLTVSSG

DNA Sequence:

gttcagctgcagcagtctggggctgaactggtggagcctggggcttcagtgaagctgtcc
tgcaagacttctggctacaccttcaccagctactggatgcactgggtgaagcagaggcct
ggacaaggccttgagtggattggagagattaatcctaccaacggttgtactagctacaat
gagaaattcaagagtaaggccacactgactgtagacaaatcctccagcacagcctacatg
caactcagcagcctgacatctgaggactctgcggtctattactgtgcaactgactactgg
ggccaaggcaccactctcacagtctcctcaggt

Data Source:

Alignment settings:

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