abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIELTQSPAIMSASLGERVTMTC	1 - 23	23
CDR-L1	TASSSVSSSYLH	24 - 35	12
LFR2	WYQQKPGSSPKLWIY	36 - 50	15
CDR-L2	STSNLAS	51 - 57	7
LFR3	GVPARFSGSGSGTSYSLTISSMEAEDAATYYC	58 - 89	32
CDR-L3	HQYHRSPYT	90 - 98	9
LFR4	FGGGTKLE	99 - 106	8
			106

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIELTQSPAIMSASLGERVTMTC------	1 - 23	23
	AbM	DIELTQSPAIMSASLGERVTMTC------	1 - 23	23
	Kabat	DIELTQSPAIMSASLGERVTMTC------	1 - 23	23
	Contact	DIELTQSPAIMSASLGERVTMTCTASSSV	1 - 29	29
	IMGT	DIELTQSPAIMSASLGERVTMTCTAS---	1 - 26	26
CDR-L1	Chothia	TASSSVSSSYLH--	24 - 35	12
	AbM	TASSSVSSSYLH--	24 - 35	12
	Kabat	TASSSVSSSYLH--	24 - 35	12
	Contact	------SSSYLHWY	30 - 37	8
	IMGT	---SSVSSSY----	27 - 33	7
LFR2	Chothia	--WYQQKPGSSPKLWIY	36 - 50	15
	AbM	--WYQQKPGSSPKLWIY	36 - 50	15
	Kabat	--WYQQKPGSSPKLWIY	36 - 50	15
	Contact	----QQKPGSSPK----	38 - 46	9
	IMGT	LHWYQQKPGSSPKLWIY	34 - 50	17
CDR-L2	Chothia	----STSNLAS	51 - 57	7
	AbM	----STSNLAS	51 - 57	7
	Kabat	----STSNLAS	51 - 57	7
	Contact	LWIYSTSNLA-	47 - 56	10
	IMGT	----ST-----	51 - 52	2
LFR3	Chothia	-----GVPARFSGSGSGTSYSLTISSMEAEDAATYYC	58 - 89	32
	AbM	-----GVPARFSGSGSGTSYSLTISSMEAEDAATYYC	58 - 89	32
	Kabat	-----GVPARFSGSGSGTSYSLTISSMEAEDAATYYC	58 - 89	32
	Contact	----SGVPARFSGSGSGTSYSLTISSMEAEDAATYYC	57 - 89	33
	IMGT	SNLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYC	53 - 89	37
CDR-L3	Chothia	HQYHRSPYT	90 - 98	9
	AbM	HQYHRSPYT	90 - 98	9
	Kabat	HQYHRSPYT	90 - 98	9
	Contact	HQYHRSPY-	90 - 97	8
	IMGT	HQYHRSPYT	90 - 98	9
LFR4	Chothia	-FGGGTKLE	99 - 106	8
	AbM	-FGGGTKLE	99 - 106	8
	Kabat	-FGGGTKLE	99 - 106	8
	Contact	TFGGGTKLE	98 - 106	9
	IMGT	-FGGGTKLE	99 - 106	8

Accession & Annotations

Accession	AAX58726.1
Source	abYsis-EMBL-IG AY869726 Submitted 01-JUN-2005 Updated 07-OCT-2005
Name	anti-BAFF immunoglobulin light chain variable region
Clone	ABL-1
Organism	Synthetic construct
Chain Type	Light
Pairing	AAX58725.1
Identical Protein Sequences	None
References	Cao P., Zhang S.Q. Submitted (28-DEC-2004) to the INSDC. Jiang Su Province Key Laboratory of Biochemistry and Molecular Biology, College of Life Science, Nanjing Normal University, Ninghai Road 122#, Nanjing, Jiansu 210097, China Cao P., Tang X.M., Guan Z.B., Diao Z.Y., Zhang S.Q. 'Production and characterization of a bacterial single-chain antibody fragment specific to B-cell-activating factor of the TNF family' Protein Expr. Purif. 43(2):157-164(2005).

Tools

Sequences

Amino Acid Sequence:

DIELTQSPAIMSASLGERVTMTCTASSSVSSSYLHWYQQKPGSSPKLWIYSTSNLASGVP
ARFSGSGSGTSYSLTISSMEAEDAATYYCHQYHRSPYTFGGGTKLE

DNA Sequence:

gacattgagctcacccagtctccagcaatcatgtctgcatctctaggggaacgggtcacc
atgacctgcactgccagctcaagtgtaagttccagttacttgcactggtaccagcagaag
ccaggatcctcccccaaactctggatttatagcacatccaacctggcttctggagtccca
gctcgcttcagtggcagtgggtctgggacctcttactctctcacaatcagcagcatggag
gctgaagatgctgccacttattactgccaccagtatcatcgttccccgtacacgttcgga
ggggggaccaagctcgag

Data Source:

Alignment settings:

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