abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	LQESGGGLVQPGGSLRLSCATSGFTFT	1 - 27	27
CDR-H1	DYYMS	28 - 32	5
HFR2	WVRQPPGKALEWLG	33 - 46	14
CDR-H2	FIRNKANGYTTEYSASVKG	47 - 65	19
HFR3	RFTISRDNSQSILYLQMNTLRAEDSATYYCAR	66 - 97	32
CDR-H3	DITL	98 - 101	4
HFR4	LGQGTTVTVSS	102 - 112	11
			112

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	LQESGGGLVQPGGSLRLSCATS-----	1 - 22	22
	AbM	LQESGGGLVQPGGSLRLSCATS-----	1 - 22	22
	Kabat	LQESGGGLVQPGGSLRLSCATSGFTFT	1 - 27	27
	Contact	LQESGGGLVQPGGSLRLSCATSGFTF-	1 - 26	26
	IMGT	LQESGGGLVQPGGSLRLSCATS-----	1 - 22	22
CDR-H1	Chothia	GFTFTDY---	23 - 29	7
	AbM	GFTFTDYYMS	23 - 32	10
	Kabat	-----DYYMS	28 - 32	5
	Contact	----TDYYMS	27 - 32	6
	IMGT	GFTFTDYY--	23 - 30	8
HFR2	Chothia	YMSWVRQPPGKALEWLGFI	30 - 48	19
	AbM	---WVRQPPGKALEWLG--	33 - 46	14
	Kabat	---WVRQPPGKALEWLG--	33 - 46	14
	Contact	---WVRQPPGKALE-----	33 - 43	11
	IMGT	-MSWVRQPPGKALEWLGF-	31 - 47	17
CDR-H2	Chothia	-----RNKANGYT---------	49 - 56	8
	AbM	---FIRNKANGYTTE-------	47 - 58	12
	Kabat	---FIRNKANGYTTEYSASVKG	47 - 65	19
	Contact	WLGFIRNKANGYTTE-------	44 - 58	15
	IMGT	----IRNKANGYTT--------	48 - 57	10
HFR3	Chothia	TEYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCAR	57 - 97	41
	AbM	--YSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCAR	59 - 97	39
	Kabat	---------RFTISRDNSQSILYLQMNTLRAEDSATYYCAR	66 - 97	32
	Contact	--YSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYC--	59 - 95	37
	IMGT	-EYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYC--	58 - 95	38
CDR-H3	Chothia	--DITL	98 - 101	4
	AbM	--DITL	98 - 101	4
	Kabat	--DITL	98 - 101	4
	Contact	ARDIT-	96 - 100	5
	IMGT	ARDITL	96 - 101	6
HFR4	Chothia	-LGQGTTVTVSS	102 - 112	11
	AbM	-LGQGTTVTVSS	102 - 112	11
	Kabat	-LGQGTTVTVSS	102 - 112	11
	Contact	LLGQGTTVTVSS	101 - 112	12
	IMGT	-LGQGTTVTVSS	102 - 112	11

Accession & Annotations

Accession	AAX58725.1
Source	abYsis-EMBL-IG AY869725 Submitted 01-JUN-2005 Updated 07-OCT-2005
Name	anti-BAFF immunoglobulin heavy chain variable region
Clone	ABL-1
Organism	Synthetic construct
Chain Type	Heavy
Pairing	AAX58726.1
Identical Protein Sequences	None
References	Cao P., Zhang S.Q. Submitted (28-DEC-2004) to the INSDC. Jiang Su Province Key Laboratory of Biochemistry and Molecular Biology, College of Life Science, Nanjing Normal University, Ninghai Road 122#, Nanjing, Jiansu 210097, China Cao P., Tang X.M., Guan Z.B., Diao Z.Y., Zhang S.Q. 'Production and characterization of a bacterial single-chain antibody fragment specific to B-cell-activating factor of the TNF family' Protein Expr. Purif. 43(2):157-164(2005).

Tools

Sequences

Amino Acid Sequence:

LQESGGGLVQPGGSLRLSCATSGFTFTDYYMSWVRQPPGKALEWLGFIRNKANGYTTEYS
ASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCARDITLLGQGTTVTVSS

DNA Sequence:

ctgcaggagtcaggaggaggcttggtacagcctgggggttctctgagactctcctgtgca
acttctgggttcaccttcactgattactacatgagctgggtccgccagcctccaggaaag
gcacttgagtggttgggttttattagaaacaaagctaatggttacacaacagagtacagt
gcatctgtgaagggtcggttcaccatctccagagataattcccaaagcatcctctatctt
caaatgaacaccctgagagctgaggacagtgccacttattactgtgcaagagatatcacc
cttctgggccaagggaccacggtcaccgtctcctca

Data Source:

Alignment settings:

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