abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
LFR1	DIVMTQTPSSLSVSAGEKVTMSC	1 - 23	23
CDR-L1	KSSQSLLNSGNQKNYLA	24 - 40	17
LFR2	WYQQKPGQPPKLLIY	41 - 55	15
CDR-L2	GASTRES	56 - 62	7
LFR3	GVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	63 - 94	32
CDR-L3	QNDYSYPFT	95 - 103	9
LFR4	FGSGPSWK	104 - 111	8
			111

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIVMTQTPSSLSVSAGEKVTMSC------	1 - 23	23
	AbM	DIVMTQTPSSLSVSAGEKVTMSC------	1 - 23	23
	Kabat	DIVMTQTPSSLSVSAGEKVTMSC------	1 - 23	23
	Contact	DIVMTQTPSSLSVSAGEKVTMSCKSSQSL	1 - 29	29
	IMGT	DIVMTQTPSSLSVSAGEKVTMSCKSS---	1 - 26	26
CDR-L1	Chothia	KSSQSLLNSGNQKNYLA--	24 - 40	17
	AbM	KSSQSLLNSGNQKNYLA--	24 - 40	17
	Kabat	KSSQSLLNSGNQKNYLA--	24 - 40	17
	Contact	------LNSGNQKNYLAWY	30 - 42	13
	IMGT	---QSLLNSGNQKNY----	27 - 38	12
LFR2	Chothia	--WYQQKPGQPPKLLIY	41 - 55	15
	AbM	--WYQQKPGQPPKLLIY	41 - 55	15
	Kabat	--WYQQKPGQPPKLLIY	41 - 55	15
	Contact	----QQKPGQPPK----	43 - 51	9
	IMGT	LAWYQQKPGQPPKLLIY	39 - 55	17
CDR-L2	Chothia	----GASTRES	56 - 62	7
	AbM	----GASTRES	56 - 62	7
	Kabat	----GASTRES	56 - 62	7
	Contact	LLIYGASTRE-	52 - 61	10
	IMGT	----GA-----	56 - 57	2
LFR3	Chothia	-----GVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	63 - 94	32
	AbM	-----GVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	63 - 94	32
	Kabat	-----GVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	63 - 94	32
	Contact	----SGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	62 - 94	33
	IMGT	STRESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYC	58 - 94	37
CDR-L3	Chothia	QNDYSYPFT	95 - 103	9
	AbM	QNDYSYPFT	95 - 103	9
	Kabat	QNDYSYPFT	95 - 103	9
	Contact	QNDYSYPF-	95 - 102	8
	IMGT	QNDYSYPFT	95 - 103	9
LFR4	Chothia	-FGSGPSWK	104 - 111	8
	AbM	-FGSGPSWK	104 - 111	8
	Kabat	-FGSGPSWK	104 - 111	8
	Contact	TFGSGPSWK	103 - 111	9
	IMGT	-FGSGPSWK	104 - 111	8

Accession & Annotations

Accession	AAG49017.1
Source	abYsis-EMBL-IG AY008758 Submitted 18-JAN-2001 Updated 09-OCT-2001
Name	anti-human C3a receptor single-chain variable fragment antibody light chain
Clone	H12
Organism	Synthetic construct
Chain Type	Light
Pairing	AAG49019.2
Identical Protein Sequences	None
References	Hawlisch H. Submitted (05-OCT-2000) to the INSDC. Medical Microbiology, Medical School Hannover, Carl-Neuberg-Str.1, Hannover, NDS 30625, Germany Hawlisch H., Muller M., Frank R., Bautsch W., Klos A., Kohl J. 'Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets' Anal. Biochem. 293(1):142-145(2001).

Tools

Sequences

Amino Acid Sequence:

DIVMTQTPSSLSVSAGEKVTMSCKSSQSLLNSGNQKNYLAWYQQKPGQPPKLLIYGASTR
ESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGPSWK

DNA Sequence:

gacattgtgatgacccagactccatcctccctgagtgtgtcagcaggagagaaggtcact
atgagctgcaagtccagtcagagtctgttaaacagtggaaatcaaaagaactacttggcc
tggtaccagcagaaaccagggcagcctcctaaactgttgatctacggggcatccactagg
gaatctggggtccctgatcgcttcacaggcagtggatctggaaccgatttcactcttacc
atcagcagtgtgcaggctgaagacctggcagtttattactgtcagaatgattatagttat
ccattcacgttcggctcgggaccaagctggaaa

Data Source:

Alignment settings:

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