abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLKESGPGLVKPSQSLSLTCSVTGYSTT	1 - 30	30
CDR-H1	SGYYWN	31 - 36	6
HFR2	WIRQFPGNKLEWMG	37 - 50	14
CDR-H2	CISYDDTNYYNPSLKN	51 - 66	16
HFR3	RISITRDTSKNQFFLKLNSVTTEDSATYYCAR	67 - 98	32
CDR-H3	DRYEFYFDY	99 - 107	9
HFR4	WGQGTTLTVSS	108 - 118	11
Tail	G	118 - 119	1
			119

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLKESGPGLVKPSQSLSLTCSVT-----	1 - 25	25
	AbM	QVQLKESGPGLVKPSQSLSLTCSVT-----	1 - 25	25
	Kabat	QVQLKESGPGLVKPSQSLSLTCSVTGYSTT	1 - 30	30
	Contact	QVQLKESGPGLVKPSQSLSLTCSVTGYST-	1 - 29	29
	IMGT	QVQLKESGPGLVKPSQSLSLTCSVT-----	1 - 25	25
CDR-H1	Chothia	GYSTTSGY---	26 - 33	8
	AbM	GYSTTSGYYWN	26 - 36	11
	Kabat	-----SGYYWN	31 - 36	6
	Contact	----TSGYYWN	30 - 36	7
	IMGT	GYSTTSGYY--	26 - 34	9
HFR2	Chothia	YWNWIRQFPGNKLEWMGCI	34 - 52	19
	AbM	---WIRQFPGNKLEWMG--	37 - 50	14
	Kabat	---WIRQFPGNKLEWMG--	37 - 50	14
	Contact	---WIRQFPGNKLE-----	37 - 47	11
	IMGT	-WNWIRQFPGNKLEWMGC-	35 - 51	17
CDR-H2	Chothia	-----SYDDT---------	53 - 57	5
	AbM	---CISYDDTNY-------	51 - 59	9
	Kabat	---CISYDDTNYYNPSLKN	51 - 66	16
	Contact	WMGCISYDDTNY-------	48 - 59	12
	IMGT	----ISYDDTN--------	52 - 58	7
HFR3	Chothia	NYYNPSLKNRISITRDTSKNQFFLKLNSVTTEDSATYYCAR	58 - 98	41
	AbM	--YNPSLKNRISITRDTSKNQFFLKLNSVTTEDSATYYCAR	60 - 98	39
	Kabat	---------RISITRDTSKNQFFLKLNSVTTEDSATYYCAR	67 - 98	32
	Contact	--YNPSLKNRISITRDTSKNQFFLKLNSVTTEDSATYYC--	60 - 96	37
	IMGT	-YYNPSLKNRISITRDTSKNQFFLKLNSVTTEDSATYYC--	59 - 96	38
CDR-H3	Chothia	--DRYEFYFDY	99 - 107	9
	AbM	--DRYEFYFDY	99 - 107	9
	Kabat	--DRYEFYFDY	99 - 107	9
	Contact	ARDRYEFYFD-	97 - 106	10
	IMGT	ARDRYEFYFDY	97 - 107	11
HFR4	Chothia	-WGQGTTLTVSS	108 - 118	11
	AbM	-WGQGTTLTVSS	108 - 118	11
	Kabat	-WGQGTTLTVSS	108 - 118	11
	Contact	YWGQGTTLTVSS	107 - 118	12
	IMGT	-WGQGTTLTVSS	108 - 118	11

Accession & Annotations

Accession	AAG49019.2
Source	abYsis-EMBL-IG AY008760 Submitted 18-JAN-2001 Updated 09-OCT-2001
Name	anti-human C3a receptor single-chain variable fragment antibody heavy chain
Clone	H12
Organism	Synthetic construct
Chain Type	Heavy
Pairing	AAG49017.1
Identical Protein Sequences	None
References	Hawlisch H. Submitted (05-OCT-2000) to the INSDC. Medical Microbiology, Medical School Hannover, Carl-Neuberg-Str.1, Hannover, NDS 30625, Germany Hawlisch H., Muller M., Frank R., Bautsch W., Klos A., Kohl J. 'Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets' Anal. Biochem. 293(1):142-145(2001). Hawlisch H. Submitted (23-JAN-2001) to the INSDC. Medical Microbiology, Medical School Hannover, Carl-Neuberg-Str.1, Hannover, NDS 30625, Germany

Tools

Sequences

Amino Acid Sequence:

QVQLKESGPGLVKPSQSLSLTCSVTGYSTTSGYYWNWIRQFPGNKLEWMGCISYDDTNYY
NPSLKNRISITRDTSKNQFFLKLNSVTTEDSATYYCARDRYEFYFDYWGQGTTLTVSSG

DNA Sequence:

caggtgcagcttaaggagtcaggacctggcctcgtgaaaccttctcagtctctgtctctc
acctgctctgtcactggctactccaccaccagtggttattactggaactggatccggcag
tttccaggaaacaaactggaatggatgggctgcataagctacgacgataccaattactac
aacccatctctcaaaaatcgaatctccatcactcgtgacacatctaagaaccagtttttc
ctgaagttgaattctgtgactactgaggactcagctacatattactgtgcaagagatagg
tacgaattctactttgactattggggccaaggcaccactctcacagtctcctcaggt

Data Source:

Alignment settings:

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