abYsis

Numbering & Regions

Comparison Organism:

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Region Sequence Details

Regions Definition

Region	Sequence Fragment	Residues	Length
HFR1	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
CDR-H1	NYKMN	31 - 35	5
HFR2	WVRQAPGKGLEWVS	36 - 49	14
CDR-H2	DISQSGASISYTGSVKG	50 - 66	17
HFR3	RFTISRDNAKNTLYLQMNSLKPEDTAVYYCAR	67 - 98	32
CDR-H3	CPAPFTRDCFDVTSTTYAY	99 - 117	19
HFR4	RGQGTQVTVSS	118 - 128	11
Tail	HHHHHHEPEA	128 - 138	10
			138

Region	Definition	Sequence Fragment	Residues	Length
HFR1	Chothia	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	AbM	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
	Kabat	QVQLQESGGGLVQPGGSLRLSCAASGFTFS	1 - 30	30
	Contact	QVQLQESGGGLVQPGGSLRLSCAASGFTF-	1 - 29	29
	IMGT	QVQLQESGGGLVQPGGSLRLSCAAS-----	1 - 25	25
CDR-H1	Chothia	GFTFSNY---	26 - 32	7
	AbM	GFTFSNYKMN	26 - 35	10
	Kabat	-----NYKMN	31 - 35	5
	Contact	----SNYKMN	30 - 35	6
	IMGT	GFTFSNYK--	26 - 33	8
HFR2	Chothia	KMNWVRQAPGKGLEWVSDI	33 - 51	19
	AbM	---WVRQAPGKGLEWVS--	36 - 49	14
	Kabat	---WVRQAPGKGLEWVS--	36 - 49	14
	Contact	---WVRQAPGKGLE-----	36 - 46	11
	IMGT	-MNWVRQAPGKGLEWVSD-	34 - 50	17
CDR-H2	Chothia	-----SQSGAS---------	52 - 57	6
	AbM	---DISQSGASIS-------	50 - 59	10
	Kabat	---DISQSGASISYTGSVKG	50 - 66	17
	Contact	WVSDISQSGASIS-------	47 - 59	13
	IMGT	----ISQSGASI--------	51 - 58	8
HFR3	Chothia	ISYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCAR	58 - 98	41
	AbM	--YTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCAR	60 - 98	39
	Kabat	---------RFTISRDNAKNTLYLQMNSLKPEDTAVYYCAR	67 - 98	32
	Contact	--YTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	60 - 96	37
	IMGT	-SYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYC--	59 - 96	38
CDR-H3	Chothia	--CPAPFTRDCFDVTSTTYAY	99 - 117	19
	AbM	--CPAPFTRDCFDVTSTTYAY	99 - 117	19
	Kabat	--CPAPFTRDCFDVTSTTYAY	99 - 117	19
	Contact	ARCPAPFTRDCFDVTSTTYA-	97 - 116	20
	IMGT	ARCPAPFTRDCFDVTSTTYAY	97 - 117	21
HFR4	Chothia	-RGQGTQVTVSS	118 - 128	11
	AbM	-RGQGTQVTVSS	118 - 128	11
	Kabat	-RGQGTQVTVSS	118 - 128	11
	Contact	YRGQGTQVTVSS	117 - 128	12
	IMGT	-RGQGTQVTVSS	118 - 128	11

Accession & Annotations

Accession	3sn6_N
Source	PDB 3sn6 Submitted 28-JUN-2011 Updated 12-JUL-2017
Name	CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX
Organism	Lama glama
Chain Type	Heavy
Pairing	None
Identical Protein Sequences	PDB: 5uz7_N 5vai_N 6b3j_N 6e3y_N 6niy_N
References	RASMUSSEN G., DEVREE T., ZOU Y., KRUSE C., CHUNG Y., KOBILKA S., THIAN S., CHAE S., PARDON E., CALINSKI D., MATHIESEN M., SHAH T., LYONS A., CAFFREY M., GELLMAN H., STEYAERT J., SKINIOTIS G., WEIS I., SUNAHARA K., KOBILKA K. 'CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX' NATURE V. 477 549 2011 ISSN 0028-0836

Tools

Sequences

Amino Acid Sequence:

QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISY
TGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQ
GTQVTVSSHHHHHHEPEA